Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU) disease, is unique amongst human pathogens in its capacity to produce a lipid toxin called mycolactone. While previous studies have demonstrated that bacterially-released mycolactone diffuses beyond infection foci, the spatiotemporal d...

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Detalles Bibliográficos
Autores principales: Colucci-Guyon, Emma, Rifflet, Aline, Saint-Auret, Sarah, da Costa, Anaëlle, Boucontet, Laurent, Laval, Thomas, Prehaud, Christophe, Blanchard, Nicolas, Levraud, Jean-Pierre, Boneca, Ivo G., Demangel, Caroline, Guenin-Macé, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710047/
https://www.ncbi.nlm.nih.gov/pubmed/33264290
http://dx.doi.org/10.1371/journal.pntd.0008878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710047/
https://www.ncbi.nlm.nih.gov/pubmed/33264290
http://dx.doi.org/10.1371/journal.pntd.0008878

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