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Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system
Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU) disease, is unique amongst human pathogens in its capacity to produce a lipid toxin called mycolactone. While previous studies have demonstrated that bacterially-released mycolactone diffuses beyond infection foci, the spatiotemporal d...
Autores principales: | Colucci-Guyon, Emma, Rifflet, Aline, Saint-Auret, Sarah, da Costa, Anaëlle, Boucontet, Laurent, Laval, Thomas, Prehaud, Christophe, Blanchard, Nicolas, Levraud, Jean-Pierre, Boneca, Ivo G., Demangel, Caroline, Guenin-Macé, Laure |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710047/ https://www.ncbi.nlm.nih.gov/pubmed/33264290 http://dx.doi.org/10.1371/journal.pntd.0008878 |
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