Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5

Sporadic inclusion body myositis (sIBM) is the most common idiopathic inflammatory myopathy, and several reports have suggested that mitochondrial abnormalities are involved in its etiology. We recruited 9 sIBM patients and found significant histological changes and an elevation of growth differenti...

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Detalles Bibliográficos
Autores principales: Oikawa, Yoshitsugu, Izumi, Rumiko, Koide, Masashi, Hagiwara, Yoshihiro, Kanzaki, Makoto, Suzuki, Naoki, Kikuchi, Koichi, Matsuhashi, Tetsuro, Akiyama, Yukako, Ichijo, Mariko, Watanabe, Shun, Toyohara, Takafumi, Suzuki, Takehiro, Mishima, Eikan, Akiyama, Yasutoshi, Ogata, Yoshiaki, Suzuki, Chitose, Hayashi, Hironori, Kodama, Eiichi N., Hayashi, Ken-ichiro, Itoi, Eiji, Aoki, Masashi, Kure, Shigeo, Abe, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710105/
https://www.ncbi.nlm.nih.gov/pubmed/33264289
http://dx.doi.org/10.1371/journal.pone.0231064

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