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Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet

Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting ~50% of all CF patients, significantly influencing pulmonary function and longevity. Yet, the complex pathogenesis of CFRD remains u...

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Detalles Bibliográficos
Autores principales:	Di Fulvio, Mauricio, Bogdani, Marika, Velasco, Myrian, McMillen, Timothy S., Ridaura, Cecilia, Kelly, Lisa, Almutairi, Mohammed M., Kursan, Shams, Sajib, Abu A., Hiriart, Marcia, Aguilar-Bryan, Lydia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710116/ https://www.ncbi.nlm.nih.gov/pubmed/33264332 http://dx.doi.org/10.1371/journal.pone.0242749

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