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Morphine‐mediated release of miR‐138 in astrocyte‐derived extracellular vesicles promotes microglial activation
Opioids, such as morphine, are the mainstay for the management of postsurgical pain. Over the last decade there has been a dramatic increase in deaths related to opioid overdose. While opioid abuse has been shown to result in increased neuroinflammation, mechanism(s) underlying this process, remain...
Autores principales: | Liao, Ke, Niu, Fang, Hu, Guoku, Yang, Lu, Dallon, Blake, Villarreal, Delaney, Buch, Shilpa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710131/ https://www.ncbi.nlm.nih.gov/pubmed/33304479 http://dx.doi.org/10.1002/jev2.12027 |
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