Pathogenic, glycolytic PD-1(+) B cells accumulate in the hypoxic RA joint

While autoantibodies are used in the diagnosis of rheumatoid arthritis (RA), the function of B cells in the inflamed joint remains elusive. Extensive flow cytometric characterization and SPICE algorithm analyses of single-cell synovial tissue from patients with RA revealed the accumulation of switch...

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Detalles Bibliográficos
Autores principales: Floudas, Achilleas, Neto, Nuno, Marzaioli, Viviana, Murray, Kieran, Moran, Barry, Monaghan, Michael G., Low, Candice, Mullan, Ronan H., Rao, Navin, Krishna, Vinod, Nagpal, Sunil, Veale, Douglas J., Fearon, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710281/
https://www.ncbi.nlm.nih.gov/pubmed/33148884
http://dx.doi.org/10.1172/jci.insight.139032

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