Elevated CCL2 causes Leydig cell malfunction in metabolic syndrome

Metabolic syndrome (MetS), which is associated with chronic inflammation, predisposes males to hypogonadism and subfertility. The underlying mechanism of these pathologies remains poorly understood. Homozygous leptin-resistant obese db/db mice are characterized by small testes, low testicular testos...

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Detalles Bibliográficos
Autores principales: Jiang, Qingkui, Maresch, Constanze C., Petry, Sebastian Friedrich, Paradowska-Dogan, Agnieszka, Bhushan, Sudhanshu, Chang, Yongsheng, Wrenzycki, Christine, Schuppe, Hans-Christian, Houska, Petr, Hartmann, Michaela F., Wudy, Stefan A., Shi, Lanbo, Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710294/
https://www.ncbi.nlm.nih.gov/pubmed/33148888
http://dx.doi.org/10.1172/jci.insight.134882

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