Bone marrow Tregs mediate stromal cell function and support hematopoiesis via IL-10

The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory and home back to the marrow. For trafficking, marrow...

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Detalles Bibliográficos
Autores principales: Camacho, Virginia, Matkins, Victoria R., Patel, Sweta B., Lever, Jeremie M., Yang, Zhengqin, Ying, Li, Landuyt, Ashley E., Dean, Emma C., George, James F., Yang, Henry, Ferrell, Paul Brent, Maynard, Craig L., Weaver, Casey T., Turnquist, Heth R., Welner, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710301/
https://www.ncbi.nlm.nih.gov/pubmed/33208555
http://dx.doi.org/10.1172/jci.insight.135681

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