Canagliflozin extends life span in genetically heterogeneous male but not female mice

Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of glucose. In the context of the mouse Interventions Testing Program, genetically he...

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Detalles Bibliográficos
Autores principales: Miller, Richard A., Harrison, David E., Allison, David B., Bogue, Molly, Debarba, Lucas, Diaz, Vivian, Fernandez, Elizabeth, Galecki, Andrzej, Garvey, W. Timothy, Jayarathne, Hashan, Kumar, Navasuja, Javors, Martin A., Ladiges, Warren C., Macchiarini, Francesca, Nelson, James, Reifsnyder, Peter, Rosenthal, Nadia A., Sadagurski, Marianna, Salmon, Adam B., Smith, Daniel L., Snyder, Jessica M., Lombard, David B., Strong, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710304/
https://www.ncbi.nlm.nih.gov/pubmed/32990681
http://dx.doi.org/10.1172/jci.insight.140019

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