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2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease
The disease, COVID-19, is caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) for which there is currently no treatment. The SARS-CoV-2 main protease (M(pro)) is an important enzyme for viral replication. Small molecules that inhibit this protease could lead to an effective COVID-19 tr...
Autores principales: | Forrestall, Katrina L., Burley, Darcy E., Cash, Meghan K., Pottie, Ian R., Darvesh, Sultan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710351/ https://www.ncbi.nlm.nih.gov/pubmed/33278462 http://dx.doi.org/10.1016/j.cbi.2020.109348 |
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