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Ganglioglioma of optic chiasma: A case report and review of literature

BACKGROUND: Gangliogliomas are neoplasms containing both astrocytic and neuronal components. We present a case of gangliogliomas of the optic chiasm, which are extremely rare pathologies. CASE DESCRIPTION: A 16-year-old female patient referred to our clinic with gradual deterioration of vision for t...

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Autores principales: Abuzayed, Bashar, Alawneh, Khaled, Al-Qawasmeh, Majdi, Al-Khatib, Sohaib, Barukba, Marwa, Raffee, Liqaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710476/
https://www.ncbi.nlm.nih.gov/pubmed/33282454
http://dx.doi.org/10.25259/SNI_496_2020
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author Abuzayed, Bashar
Alawneh, Khaled
Al-Qawasmeh, Majdi
Al-Khatib, Sohaib
Barukba, Marwa
Raffee, Liqaa
author_facet Abuzayed, Bashar
Alawneh, Khaled
Al-Qawasmeh, Majdi
Al-Khatib, Sohaib
Barukba, Marwa
Raffee, Liqaa
author_sort Abuzayed, Bashar
collection PubMed
description BACKGROUND: Gangliogliomas are neoplasms containing both astrocytic and neuronal components. We present a case of gangliogliomas of the optic chiasm, which are extremely rare pathologies. CASE DESCRIPTION: A 16-year-old female patient referred to our clinic with gradual deterioration of vision for the age of 1 year mostly in the right eye. Ophthalmic examination confirmed reduced visual acuity with only perception of light in the left eye. Brain magnetic resonance imaging showed a solid mass lesion involving the hypothalamus and the optic chiasm, which was hypointense on T1-weighted images, hyperintense on T2-WI, and marked homogenous contrast enhancement. The patient was operated and bulging of the optic chiasm and the site of lamina terminalis was seen. Subtotal resection of the tumor was achieved. Histopathological examination revealed ganglioglioma (WHO Grade I). Follow-up of the patient was for 3 years and 8 months with stable neurologic and radiologic findings. CONCLUSION: To the best of our knowledge, 20 cases, including ours, have been reported in the literature and a presurgical diagnosis of ganglioglioma is very infrequent with confused radiologically with low-grade pilocytic astrocytomas.
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spelling pubmed-77104762020-12-03 Ganglioglioma of optic chiasma: A case report and review of literature Abuzayed, Bashar Alawneh, Khaled Al-Qawasmeh, Majdi Al-Khatib, Sohaib Barukba, Marwa Raffee, Liqaa Surg Neurol Int Case Report BACKGROUND: Gangliogliomas are neoplasms containing both astrocytic and neuronal components. We present a case of gangliogliomas of the optic chiasm, which are extremely rare pathologies. CASE DESCRIPTION: A 16-year-old female patient referred to our clinic with gradual deterioration of vision for the age of 1 year mostly in the right eye. Ophthalmic examination confirmed reduced visual acuity with only perception of light in the left eye. Brain magnetic resonance imaging showed a solid mass lesion involving the hypothalamus and the optic chiasm, which was hypointense on T1-weighted images, hyperintense on T2-WI, and marked homogenous contrast enhancement. The patient was operated and bulging of the optic chiasm and the site of lamina terminalis was seen. Subtotal resection of the tumor was achieved. Histopathological examination revealed ganglioglioma (WHO Grade I). Follow-up of the patient was for 3 years and 8 months with stable neurologic and radiologic findings. CONCLUSION: To the best of our knowledge, 20 cases, including ours, have been reported in the literature and a presurgical diagnosis of ganglioglioma is very infrequent with confused radiologically with low-grade pilocytic astrocytomas. Scientific Scholar 2020-11-18 /pmc/articles/PMC7710476/ /pubmed/33282454 http://dx.doi.org/10.25259/SNI_496_2020 Text en Copyright: © 2020 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Abuzayed, Bashar
Alawneh, Khaled
Al-Qawasmeh, Majdi
Al-Khatib, Sohaib
Barukba, Marwa
Raffee, Liqaa
Ganglioglioma of optic chiasma: A case report and review of literature
title Ganglioglioma of optic chiasma: A case report and review of literature
title_full Ganglioglioma of optic chiasma: A case report and review of literature
title_fullStr Ganglioglioma of optic chiasma: A case report and review of literature
title_full_unstemmed Ganglioglioma of optic chiasma: A case report and review of literature
title_short Ganglioglioma of optic chiasma: A case report and review of literature
title_sort ganglioglioma of optic chiasma: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710476/
https://www.ncbi.nlm.nih.gov/pubmed/33282454
http://dx.doi.org/10.25259/SNI_496_2020
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