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BMSC-Exosomes Carry Mutant HIF-1α for Improving Angiogenesis and Osteogenesis in Critical-Sized Calvarial Defects

Repair and reconstruction of critical-sized bone defects has always been a difficult task in orthopedics. Hypoxia inducible factor-1α (HIF-1α) plays an important role in bone defect repair, it has the dual function of promoting osteogenesis and vascular regeneration, but it is quickly degraded by th...

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Detalles Bibliográficos
Autores principales:	Ying, Chenting, Wang, Rui, Wang, Zhenlin, Tao, Jie, Yin, Wenjing, Zhang, Jieyuan, Yi, Chengqing, Qi, Xin, Han, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710518/ https://www.ncbi.nlm.nih.gov/pubmed/33330411 http://dx.doi.org/10.3389/fbioe.2020.565561

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