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Radiation-induced DNA damage and repair effects on 3D genome organization

The three-dimensional structure of chromosomes plays an important role in gene expression regulation and also influences the repair of radiation-induced DNA damage. Genomic aberrations that disrupt chromosome spatial domains can lead to diseases including cancer, but how the 3D genome structure resp...

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Detalles Bibliográficos
Autores principales: Sanders, Jacob T., Freeman, Trevor F., Xu, Yang, Golloshi, Rosela, Stallard, Mary A., Hill, Ashtyn M., San Martin, Rebeca, Balajee, Adayabalam S., McCord, Rachel Patton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710719/
https://www.ncbi.nlm.nih.gov/pubmed/33268790
http://dx.doi.org/10.1038/s41467-020-20047-w