Adaptive selection drives TRPP3 loss-of-function in an Ethiopian population

TRPP3 (also called PKD2L1) is a nonselective, cation-permeable channel activated by multiple stimuli, including extracellular pH changes. TRPP3 had been considered a candidate for sour sensor in humans, due to its high expression in a subset of tongue receptor cells detecting sour, along with its me...

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Detalles Bibliográficos
Autores principales: Walsh, Sandra, Izquierdo-Serra, Mercè, Acosta, Sandra, Edo, Albert, Lloret, María, Moret, Roser, Bosch, Elena, Oliva, Baldo, Bertranpetit, Jaume, Fernández-Fernández, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710729/
https://www.ncbi.nlm.nih.gov/pubmed/33268808
http://dx.doi.org/10.1038/s41598-020-78081-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710729/
https://www.ncbi.nlm.nih.gov/pubmed/33268808
http://dx.doi.org/10.1038/s41598-020-78081-z

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