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Adaptive selection drives TRPP3 loss-of-function in an Ethiopian population
TRPP3 (also called PKD2L1) is a nonselective, cation-permeable channel activated by multiple stimuli, including extracellular pH changes. TRPP3 had been considered a candidate for sour sensor in humans, due to its high expression in a subset of tongue receptor cells detecting sour, along with its me...
Autores principales: | Walsh, Sandra, Izquierdo-Serra, Mercè, Acosta, Sandra, Edo, Albert, Lloret, María, Moret, Roser, Bosch, Elena, Oliva, Baldo, Bertranpetit, Jaume, Fernández-Fernández, José Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710729/ https://www.ncbi.nlm.nih.gov/pubmed/33268808 http://dx.doi.org/10.1038/s41598-020-78081-z |
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