A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation

DNA 5-hydroxymethylcytosine (5hmC) modification is known to be associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development and in human diseases. However, the lack of genome-wide 5hmC profiles in different human tiss...

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Detalles Bibliográficos
Autores principales: Cui, Xiao-Long, Nie, Ji, Ku, Jeremy, Dougherty, Urszula, West-Szymanski, Diana C., Collin, Francois, Ellison, Christopher K., Sieh, Laura, Ning, Yuhong, Deng, Zifeng, Zhao, Carolyn W. T., Bergamaschi, Anna, Pekow, Joel, Wei, Jiangbo, Beadell, Alana V., Zhang, Zhou, Sharma, Geeta, Talwar, Raman, Arensdorf, Patrick, Karpus, Jason, Goel, Ajay, Bissonnette, Marc, Zhang, Wei, Levy, Samuel, He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710742/
https://www.ncbi.nlm.nih.gov/pubmed/33268789
http://dx.doi.org/10.1038/s41467-020-20001-w

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