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Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
Annotations of evolutionary sequence constraint based on multi-species genome alignments and genome-wide maps of epigenomic marks and transcription factor binding provide important complementary information for understanding the human genome and genetic variation. Here we developed the Constrained N...
Autores principales: | Grujic, Olivera, Phung, Tanya N., Kwon, Soo Bin, Arneson, Adriana, Lee, Yuju, Lohmueller, Kirk E., Ernst, Jason |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710766/ https://www.ncbi.nlm.nih.gov/pubmed/33268804 http://dx.doi.org/10.1038/s41467-020-19962-9 |
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