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Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations

Annotations of evolutionary sequence constraint based on multi-species genome alignments and genome-wide maps of epigenomic marks and transcription factor binding provide important complementary information for understanding the human genome and genetic variation. Here we developed the Constrained N...

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Detalles Bibliográficos
Autores principales: Grujic, Olivera, Phung, Tanya N., Kwon, Soo Bin, Arneson, Adriana, Lee, Yuju, Lohmueller, Kirk E., Ernst, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710766/
https://www.ncbi.nlm.nih.gov/pubmed/33268804
http://dx.doi.org/10.1038/s41467-020-19962-9

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