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Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?

Graphene, a wonder material, has made far-reaching developments in many different fields such as materials science, electronics, condensed physics, quantum physics, energy systems, etc. Since its discovery in 2004, extensive studies have been done for understanding its physical and chemical properti...

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Autores principales: Hoseini-Ghahfarokhi, Mojtaba, Mirkiani, Soroush, Mozaffari, Naeimeh, Abdolahi Sadatlu, Mohamad Amin, Ghasemi, Amir, Abbaspour, Somayeh, Akbarian, Mohsen, Farjadian, Fatemeh, Karimi, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710865/
https://www.ncbi.nlm.nih.gov/pubmed/33281443
http://dx.doi.org/10.2147/IJN.S265876
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author Hoseini-Ghahfarokhi, Mojtaba
Mirkiani, Soroush
Mozaffari, Naeimeh
Abdolahi Sadatlu, Mohamad Amin
Ghasemi, Amir
Abbaspour, Somayeh
Akbarian, Mohsen
Farjadian, Fatemeh
Karimi, Mahdi
author_facet Hoseini-Ghahfarokhi, Mojtaba
Mirkiani, Soroush
Mozaffari, Naeimeh
Abdolahi Sadatlu, Mohamad Amin
Ghasemi, Amir
Abbaspour, Somayeh
Akbarian, Mohsen
Farjadian, Fatemeh
Karimi, Mahdi
author_sort Hoseini-Ghahfarokhi, Mojtaba
collection PubMed
description Graphene, a wonder material, has made far-reaching developments in many different fields such as materials science, electronics, condensed physics, quantum physics, energy systems, etc. Since its discovery in 2004, extensive studies have been done for understanding its physical and chemical properties. Owing to its unique characteristics, it has rapidly became a potential candidate for nano-bio researchers to explore its usage in biomedical applications. In the last decade, remarkable efforts have been devoted to investigating the biomedical utilization of graphene and graphene-based materials, especially in smart drug and gene delivery as well as cancer therapy. Inspired by a great number of successful graphene-based materials integrations into the biomedical area, here we summarize the most recent developments made about graphene applications in biomedicine. In this paper, we review the up-to-date advances of graphene-based materials in drug delivery applications, specifically targeted drug/ gene delivery, delivery of antitumor drugs, controlled and stimuli-responsive drug release, photodynamic therapy applications and optical imaging and theranostics, as well as investigating the future trends and succeeding challenges in this topic to provide an outlook for future researches.
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spelling pubmed-77108652020-12-03 Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat? Hoseini-Ghahfarokhi, Mojtaba Mirkiani, Soroush Mozaffari, Naeimeh Abdolahi Sadatlu, Mohamad Amin Ghasemi, Amir Abbaspour, Somayeh Akbarian, Mohsen Farjadian, Fatemeh Karimi, Mahdi Int J Nanomedicine Review Graphene, a wonder material, has made far-reaching developments in many different fields such as materials science, electronics, condensed physics, quantum physics, energy systems, etc. Since its discovery in 2004, extensive studies have been done for understanding its physical and chemical properties. Owing to its unique characteristics, it has rapidly became a potential candidate for nano-bio researchers to explore its usage in biomedical applications. In the last decade, remarkable efforts have been devoted to investigating the biomedical utilization of graphene and graphene-based materials, especially in smart drug and gene delivery as well as cancer therapy. Inspired by a great number of successful graphene-based materials integrations into the biomedical area, here we summarize the most recent developments made about graphene applications in biomedicine. In this paper, we review the up-to-date advances of graphene-based materials in drug delivery applications, specifically targeted drug/ gene delivery, delivery of antitumor drugs, controlled and stimuli-responsive drug release, photodynamic therapy applications and optical imaging and theranostics, as well as investigating the future trends and succeeding challenges in this topic to provide an outlook for future researches. Dove 2020-11-27 /pmc/articles/PMC7710865/ /pubmed/33281443 http://dx.doi.org/10.2147/IJN.S265876 Text en © 2020 Hoseini-Ghahfarokhi et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Hoseini-Ghahfarokhi, Mojtaba
Mirkiani, Soroush
Mozaffari, Naeimeh
Abdolahi Sadatlu, Mohamad Amin
Ghasemi, Amir
Abbaspour, Somayeh
Akbarian, Mohsen
Farjadian, Fatemeh
Karimi, Mahdi
Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
title Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
title_full Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
title_fullStr Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
title_full_unstemmed Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
title_short Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
title_sort applications of graphene and graphene oxide in smart drug/gene delivery: is the world still flat?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710865/
https://www.ncbi.nlm.nih.gov/pubmed/33281443
http://dx.doi.org/10.2147/IJN.S265876
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