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Down-Regulation of Lnc-CYP7A1-1 Rejuvenates Aged Human Mesenchymal Stem Cells to Improve Their Efficacy for Heart Repair Through SYNE1

BACKGROUND: Several long non-coding RNAs (lncRNAs) have been associated with cell senescence, termed senescence-associated lncRNAs (SAL-RNAs). However, the mechanisms involved for SAL-RNAs in aging are not fully elucidated. In the present study, we investigated the effects of SAL-RNAs on aged human...

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Detalles Bibliográficos
Autores principales:	Dong, Jun, Liu, Jianwei, Wen, Yueqiang, Tobin, Stephanie W., Zhang, Chongyu, Zheng, Huiling, Huang, Zehan, Feng, Yongtao, Zhang, Dongcheng, Liu, Shiming, Zhang, Zhenhui, Li, Jiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710953/ https://www.ncbi.nlm.nih.gov/pubmed/33330489 http://dx.doi.org/10.3389/fcell.2020.600304

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