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Relationship of Change in Plasma Clozapine/N-desmethylclozapine Ratio with Cognitive Performance in Patients with Schizophrenia

OBJECTIVE: The clozapine/N-desmethylclozapine (NDMC) ratio is proposed to be used as a predictor of cognitive performance in clozapine-treated patients, as its principal metabolite, NDMC, has an opposite action with clozapine on the cholinergic system. The aim of this study is to determine whether c...

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Detalles Bibliográficos
Autores principales: Park, Royun, Kim, Seoyoung, Kim, Euitae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711124/
https://www.ncbi.nlm.nih.gov/pubmed/33198433
http://dx.doi.org/10.30773/pi.2020.0306

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