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A fractional order approach to modeling and simulations of the novel COVID-19

The novel coronavirus (SARS-CoV-2), or COVID-19, has emerged and spread at fast speed globally; the disease has become an unprecedented threat to public health worldwide. It is one of the greatest public health challenges in modern times, with no proven cure or vaccine. In this paper, our focus is o...

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Autores principales: Owusu-Mensah, Isaac, Akinyemi, Lanre, Oduro, Bismark, Iyiola, Olaniyi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711272/
https://www.ncbi.nlm.nih.gov/pubmed/33288983
http://dx.doi.org/10.1186/s13662-020-03141-7
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author Owusu-Mensah, Isaac
Akinyemi, Lanre
Oduro, Bismark
Iyiola, Olaniyi S.
author_facet Owusu-Mensah, Isaac
Akinyemi, Lanre
Oduro, Bismark
Iyiola, Olaniyi S.
author_sort Owusu-Mensah, Isaac
collection PubMed
description The novel coronavirus (SARS-CoV-2), or COVID-19, has emerged and spread at fast speed globally; the disease has become an unprecedented threat to public health worldwide. It is one of the greatest public health challenges in modern times, with no proven cure or vaccine. In this paper, our focus is on a fractional order approach to modeling and simulations of the novel COVID-19. We introduce a fractional type susceptible–exposed–infected–recovered (SEIR) model to gain insight into the ongoing pandemic. Our proposed model incorporates transmission rate, testing rates, and transition rate (from asymptomatic to symptomatic population groups) for a holistic study of the coronavirus disease. The impacts of these parameters on the dynamics of the solution profiles for the disease are simulated and discussed in detail. Furthermore, across all the different parameters, the effects of the fractional order derivative are also simulated and discussed in detail. Various simulations carried out enable us gain deep insights into the dynamics of the spread of COVID-19. The simulation results confirm that fractional calculus is an appropriate tool in modeling the spread of a complex infectious disease such as the novel COVID-19. In the absence of vaccine and treatment, our analysis strongly supports the significance reduction in the transmission rate as a valuable strategy to curb the spread of the virus. Our results suggest that tracing and moving testing up has an important benefit. It reduces the number of infected individuals in the general public and thereby reduces the spread of the pandemic. Once the infected individuals are identified and isolated, the interaction between susceptible and infected individuals diminishes and transmission reduces. Furthermore, aggressive testing is also highly recommended.
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spelling pubmed-77112722020-12-03 A fractional order approach to modeling and simulations of the novel COVID-19 Owusu-Mensah, Isaac Akinyemi, Lanre Oduro, Bismark Iyiola, Olaniyi S. Adv Differ Equ Research The novel coronavirus (SARS-CoV-2), or COVID-19, has emerged and spread at fast speed globally; the disease has become an unprecedented threat to public health worldwide. It is one of the greatest public health challenges in modern times, with no proven cure or vaccine. In this paper, our focus is on a fractional order approach to modeling and simulations of the novel COVID-19. We introduce a fractional type susceptible–exposed–infected–recovered (SEIR) model to gain insight into the ongoing pandemic. Our proposed model incorporates transmission rate, testing rates, and transition rate (from asymptomatic to symptomatic population groups) for a holistic study of the coronavirus disease. The impacts of these parameters on the dynamics of the solution profiles for the disease are simulated and discussed in detail. Furthermore, across all the different parameters, the effects of the fractional order derivative are also simulated and discussed in detail. Various simulations carried out enable us gain deep insights into the dynamics of the spread of COVID-19. The simulation results confirm that fractional calculus is an appropriate tool in modeling the spread of a complex infectious disease such as the novel COVID-19. In the absence of vaccine and treatment, our analysis strongly supports the significance reduction in the transmission rate as a valuable strategy to curb the spread of the virus. Our results suggest that tracing and moving testing up has an important benefit. It reduces the number of infected individuals in the general public and thereby reduces the spread of the pandemic. Once the infected individuals are identified and isolated, the interaction between susceptible and infected individuals diminishes and transmission reduces. Furthermore, aggressive testing is also highly recommended. Springer International Publishing 2020-12-03 2020 /pmc/articles/PMC7711272/ /pubmed/33288983 http://dx.doi.org/10.1186/s13662-020-03141-7 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research
Owusu-Mensah, Isaac
Akinyemi, Lanre
Oduro, Bismark
Iyiola, Olaniyi S.
A fractional order approach to modeling and simulations of the novel COVID-19
title A fractional order approach to modeling and simulations of the novel COVID-19
title_full A fractional order approach to modeling and simulations of the novel COVID-19
title_fullStr A fractional order approach to modeling and simulations of the novel COVID-19
title_full_unstemmed A fractional order approach to modeling and simulations of the novel COVID-19
title_short A fractional order approach to modeling and simulations of the novel COVID-19
title_sort fractional order approach to modeling and simulations of the novel covid-19
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711272/
https://www.ncbi.nlm.nih.gov/pubmed/33288983
http://dx.doi.org/10.1186/s13662-020-03141-7
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