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An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice

OBJECTIVE: Portulaca oleracea L. (PO) is abundantly found in Iran and is used in both nutritional and traditional medicine. Delaying thirst is one of the uses of the medicinal product of this plant which has been emphasized in Iranian traditional medicine though it was not proven scientifically. Acc...

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Autores principales: Jafari Foutami, Isa, Hosseini Yekta, Nafiseh, Mehri, Mozhgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711290/
https://www.ncbi.nlm.nih.gov/pubmed/33299818
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author Jafari Foutami, Isa
Hosseini Yekta, Nafiseh
Mehri, Mozhgan
author_facet Jafari Foutami, Isa
Hosseini Yekta, Nafiseh
Mehri, Mozhgan
author_sort Jafari Foutami, Isa
collection PubMed
description OBJECTIVE: Portulaca oleracea L. (PO) is abundantly found in Iran and is used in both nutritional and traditional medicine. Delaying thirst is one of the uses of the medicinal product of this plant which has been emphasized in Iranian traditional medicine though it was not proven scientifically. Accordingly, the present study aimed to investigate the effect of PO product on thirst. MATERIALS AND METHODS: In this research, two main Set of experiments were considered: acute water deprivation group and chronic water restriction group. The urine parameters analyzed were osmolality, and sodium, and potassium concentration, and blood parameters evaluated included blood urea nitrogen, creatinine, osmolality, and sodium, and potassium concentration. The PO dosages were 50, 100 and 200 mg/kg. RESULTS: The findings showed that the effects of PO 100 and 200 (mg/kg) on blood and urine parameters were greater than that of PO 50 mg/kg, but there were no significant differences between them. CONCLUSION: In general, these findings indicate that PO extract can play an important role in reducing thirst symptoms most likely by affecting intra- and extra-cellular environments. Also, it is recommended to study the beneficial effects of this plant on diseases that lead to hypokalemia or blood potassium depletion.
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spelling pubmed-77112902020-12-08 An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice Jafari Foutami, Isa Hosseini Yekta, Nafiseh Mehri, Mozhgan Avicenna J Phytomed Original Research Article OBJECTIVE: Portulaca oleracea L. (PO) is abundantly found in Iran and is used in both nutritional and traditional medicine. Delaying thirst is one of the uses of the medicinal product of this plant which has been emphasized in Iranian traditional medicine though it was not proven scientifically. Accordingly, the present study aimed to investigate the effect of PO product on thirst. MATERIALS AND METHODS: In this research, two main Set of experiments were considered: acute water deprivation group and chronic water restriction group. The urine parameters analyzed were osmolality, and sodium, and potassium concentration, and blood parameters evaluated included blood urea nitrogen, creatinine, osmolality, and sodium, and potassium concentration. The PO dosages were 50, 100 and 200 mg/kg. RESULTS: The findings showed that the effects of PO 100 and 200 (mg/kg) on blood and urine parameters were greater than that of PO 50 mg/kg, but there were no significant differences between them. CONCLUSION: In general, these findings indicate that PO extract can play an important role in reducing thirst symptoms most likely by affecting intra- and extra-cellular environments. Also, it is recommended to study the beneficial effects of this plant on diseases that lead to hypokalemia or blood potassium depletion. Mashhad University of Medical Sciences 2020 /pmc/articles/PMC7711290/ /pubmed/33299818 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Article
Jafari Foutami, Isa
Hosseini Yekta, Nafiseh
Mehri, Mozhgan
An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
title An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
title_full An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
title_fullStr An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
title_full_unstemmed An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
title_short An investigation of the effect of purslane (Portulaca oleracea L.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
title_sort investigation of the effect of purslane (portulaca oleracea l.) extract on body resistance toward thirst by examining urine and blood variables in laboratory mice
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711290/
https://www.ncbi.nlm.nih.gov/pubmed/33299818
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