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Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps

Fungal infections are an increasingly important public health issue, yet accurate statistics on fungal burden worldwide and in Kuwait are scarce. Here we estimate the incidence and prevalence of fungal infections in Kuwait. Population statistics from 2018 collected by the Public Authority for Civil...

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Autores principales: Alfouzan, Wadha, Al-Wathiqi, Faten, Altawalah, Haya, Asadzadeh, Mohammad, Khan, Ziauddin, Denning, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711545/
https://www.ncbi.nlm.nih.gov/pubmed/33233367
http://dx.doi.org/10.3390/jof6040306
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author Alfouzan, Wadha
Al-Wathiqi, Faten
Altawalah, Haya
Asadzadeh, Mohammad
Khan, Ziauddin
Denning, David W.
author_facet Alfouzan, Wadha
Al-Wathiqi, Faten
Altawalah, Haya
Asadzadeh, Mohammad
Khan, Ziauddin
Denning, David W.
author_sort Alfouzan, Wadha
collection PubMed
description Fungal infections are an increasingly important public health issue, yet accurate statistics on fungal burden worldwide and in Kuwait are scarce. Here we estimate the incidence and prevalence of fungal infections in Kuwait. Population statistics from 2018 collected by the Public Authority for Civil Information were used, as well as data from the Ministry of Health. A literature search for Kuwait data on mycotic diseases and population at risk (chronic obstructive pulmonary disease, HIV infection/AIDS, cancer, and transplant patients) was conducted. The population in 2018 was estimated at 4,226,920 million people: 1,303,246 million Kuwaitis and 2,923,674 million expatriates. We determined the annual burden of serious fungal infections number (per 100,000) from high to low based on earlier reported fungal rates for populations at risk: recurrent Candida vaginitis 54,842 (2595); severe asthma with fungal sensitisation 10,411 (246); allergic bronchopulmonary aspergillosis, 7887 (187); chronic pulmonary aspergillosis 995 (21.3); invasive aspergillosis 704 (16.7); fungal keratitis 654 (15.5); candidaemia 288 (6.8); Candida peritonitis 63 (3.5) and oesophageal candidiasis in HIV 33 (0.8). Besides identifying rising new risk groups and expanding reports on antifungal resistance, surveillance programs and further epidemiological studies are needed to achieve more precise assessments of fungal disease epidemiology and correlated morbidity and mortality.
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spelling pubmed-77115452020-12-04 Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps Alfouzan, Wadha Al-Wathiqi, Faten Altawalah, Haya Asadzadeh, Mohammad Khan, Ziauddin Denning, David W. J Fungi (Basel) Article Fungal infections are an increasingly important public health issue, yet accurate statistics on fungal burden worldwide and in Kuwait are scarce. Here we estimate the incidence and prevalence of fungal infections in Kuwait. Population statistics from 2018 collected by the Public Authority for Civil Information were used, as well as data from the Ministry of Health. A literature search for Kuwait data on mycotic diseases and population at risk (chronic obstructive pulmonary disease, HIV infection/AIDS, cancer, and transplant patients) was conducted. The population in 2018 was estimated at 4,226,920 million people: 1,303,246 million Kuwaitis and 2,923,674 million expatriates. We determined the annual burden of serious fungal infections number (per 100,000) from high to low based on earlier reported fungal rates for populations at risk: recurrent Candida vaginitis 54,842 (2595); severe asthma with fungal sensitisation 10,411 (246); allergic bronchopulmonary aspergillosis, 7887 (187); chronic pulmonary aspergillosis 995 (21.3); invasive aspergillosis 704 (16.7); fungal keratitis 654 (15.5); candidaemia 288 (6.8); Candida peritonitis 63 (3.5) and oesophageal candidiasis in HIV 33 (0.8). Besides identifying rising new risk groups and expanding reports on antifungal resistance, surveillance programs and further epidemiological studies are needed to achieve more precise assessments of fungal disease epidemiology and correlated morbidity and mortality. MDPI 2020-11-21 /pmc/articles/PMC7711545/ /pubmed/33233367 http://dx.doi.org/10.3390/jof6040306 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alfouzan, Wadha
Al-Wathiqi, Faten
Altawalah, Haya
Asadzadeh, Mohammad
Khan, Ziauddin
Denning, David W.
Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps
title Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps
title_full Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps
title_fullStr Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps
title_full_unstemmed Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps
title_short Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps
title_sort human fungal infections in kuwait—burden and diagnostic gaps
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711545/
https://www.ncbi.nlm.nih.gov/pubmed/33233367
http://dx.doi.org/10.3390/jof6040306
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