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Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus)
Bromadiolone is a second generation anticoagulant rodenticide (SGAR) used to control pest rodents worldwide. SGARs are frequently involved in secondary poisoning in rodent predators due to their persistence and toxicity. This study aims to evaluate the persistence of bromadiolone in liver at differe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711720/ https://www.ncbi.nlm.nih.gov/pubmed/33171863 http://dx.doi.org/10.3390/toxics8040098 |
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author | Valverde, Irene Espín, Silvia Gómez-Ramírez, Pilar Navas, Isabel Sánchez-Virosta, Pablo Torres-Chaparro, María Y. Jiménez, Pedro María-Mojica, Pedro García-Fernández, Antonio J. |
author_facet | Valverde, Irene Espín, Silvia Gómez-Ramírez, Pilar Navas, Isabel Sánchez-Virosta, Pablo Torres-Chaparro, María Y. Jiménez, Pedro María-Mojica, Pedro García-Fernández, Antonio J. |
author_sort | Valverde, Irene |
collection | PubMed |
description | Bromadiolone is a second generation anticoagulant rodenticide (SGAR) used to control pest rodents worldwide. SGARs are frequently involved in secondary poisoning in rodent predators due to their persistence and toxicity. This study aims to evaluate the persistence of bromadiolone in liver at different stages of carcass decomposition in experimentally-dosed common kestrels (Falco tinnunculus) to understand the possibility of detecting bromadiolone in cases of wildlife poisoning and the potential risk of tertiary poisoning. Twelve individuals were divided into the bromadiolone-dose group (dosed with 55 mg/kg b.w) and the control group. Hepatic bromadiolone concentrations found in each stage of decomposition were: 3000, 2891, 4804, 4245, 8848, and 756 ng/g dry weight at 1–2 h (fresh carcass), 24 h (moderate decomposition), 72 h, 96 h (advanced decomposition), seven days (very advanced decomposition), and 15 days (initial skeletal reduction) after death, respectively. Liver bromadiolone concentrations in carcasses remained relatively stable over the first four days and raised on day 7 of decomposition under the specific conditions of this experiment, presenting a risk of causing tertiary poisoning. However, at the initial skeletal reduction stage, liver bromadiolone concentration declined, which should be considered to interpret toxicological analyses and for proper diagnosis. This experimental study provides for the first time some light to better understand the degradation of SGARs in carcasses in the wild. |
format | Online Article Text |
id | pubmed-7711720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77117202020-12-04 Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) Valverde, Irene Espín, Silvia Gómez-Ramírez, Pilar Navas, Isabel Sánchez-Virosta, Pablo Torres-Chaparro, María Y. Jiménez, Pedro María-Mojica, Pedro García-Fernández, Antonio J. Toxics Article Bromadiolone is a second generation anticoagulant rodenticide (SGAR) used to control pest rodents worldwide. SGARs are frequently involved in secondary poisoning in rodent predators due to their persistence and toxicity. This study aims to evaluate the persistence of bromadiolone in liver at different stages of carcass decomposition in experimentally-dosed common kestrels (Falco tinnunculus) to understand the possibility of detecting bromadiolone in cases of wildlife poisoning and the potential risk of tertiary poisoning. Twelve individuals were divided into the bromadiolone-dose group (dosed with 55 mg/kg b.w) and the control group. Hepatic bromadiolone concentrations found in each stage of decomposition were: 3000, 2891, 4804, 4245, 8848, and 756 ng/g dry weight at 1–2 h (fresh carcass), 24 h (moderate decomposition), 72 h, 96 h (advanced decomposition), seven days (very advanced decomposition), and 15 days (initial skeletal reduction) after death, respectively. Liver bromadiolone concentrations in carcasses remained relatively stable over the first four days and raised on day 7 of decomposition under the specific conditions of this experiment, presenting a risk of causing tertiary poisoning. However, at the initial skeletal reduction stage, liver bromadiolone concentration declined, which should be considered to interpret toxicological analyses and for proper diagnosis. This experimental study provides for the first time some light to better understand the degradation of SGARs in carcasses in the wild. MDPI 2020-11-07 /pmc/articles/PMC7711720/ /pubmed/33171863 http://dx.doi.org/10.3390/toxics8040098 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Valverde, Irene Espín, Silvia Gómez-Ramírez, Pilar Navas, Isabel Sánchez-Virosta, Pablo Torres-Chaparro, María Y. Jiménez, Pedro María-Mojica, Pedro García-Fernández, Antonio J. Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) |
title | Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) |
title_full | Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) |
title_fullStr | Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) |
title_full_unstemmed | Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) |
title_short | Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus) |
title_sort | temporal persistence of bromadiolone in decomposing bodies of common kestrel (falco tinnunculus) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711720/ https://www.ncbi.nlm.nih.gov/pubmed/33171863 http://dx.doi.org/10.3390/toxics8040098 |
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