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Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values

Pathological analysis of ovarian cysts shows specific fluid characteristics that cannot be standardly evaluated on computer tomography (CT) examinations. This study aimed to assess the ovarian cysts’ fluid attenuation values on the native (Np), arterial (Ap), and venous (Vp) contrast phases of seven...

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Autores principales: Lupean, Roxana-Adelina, Ștefan, Paul-Andrei, Oancea, Mihaela Daniela, Măluțan, Andrei Mihai, Lebovici, Andrei, Pușcaș, Marius Emil, Csutak, Csaba, Mihu, Carmen Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711840/
https://www.ncbi.nlm.nih.gov/pubmed/33066370
http://dx.doi.org/10.3390/healthcare8040398
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author Lupean, Roxana-Adelina
Ștefan, Paul-Andrei
Oancea, Mihaela Daniela
Măluțan, Andrei Mihai
Lebovici, Andrei
Pușcaș, Marius Emil
Csutak, Csaba
Mihu, Carmen Mihaela
author_facet Lupean, Roxana-Adelina
Ștefan, Paul-Andrei
Oancea, Mihaela Daniela
Măluțan, Andrei Mihai
Lebovici, Andrei
Pușcaș, Marius Emil
Csutak, Csaba
Mihu, Carmen Mihaela
author_sort Lupean, Roxana-Adelina
collection PubMed
description Pathological analysis of ovarian cysts shows specific fluid characteristics that cannot be standardly evaluated on computer tomography (CT) examinations. This study aimed to assess the ovarian cysts’ fluid attenuation values on the native (Np), arterial (Ap), and venous (Vp) contrast phases of seventy patients with ovarian cysts who underwent CT examinations and were retrospectively included in this study. Patients were divided according to their final diagnosis into the benign group (n = 32) and malignant group (n = 38; of which 27 were primary and 11 were secondary lesions). Two radiologists measured the fluid attenuation values on each contrast phase, and the average values were used to discriminate between benign and malignant groups and primary tumors and metastases via univariate, multivariate, multiple regression, and receiver operating characteristics analyses. The Ap densities (p = 0.0002) were independently associated with malignant cysts. Based on the densities measured on all three phases, neoplastic lesions could be diagnosed with 89.47% sensitivity and 62.5% specificity. The Np densities (p = 0.0005) were able to identify metastases with 90.91% sensitivity and 70.37% specificity, while the combined densities of all three phases diagnosed secondary lesions with 72.73% sensitivity and 92.59% specificity. The ovarian cysts’ fluid densities could function as an adjuvant criterion to the classic CT evaluation of ovarian cysts.
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spelling pubmed-77118402020-12-04 Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values Lupean, Roxana-Adelina Ștefan, Paul-Andrei Oancea, Mihaela Daniela Măluțan, Andrei Mihai Lebovici, Andrei Pușcaș, Marius Emil Csutak, Csaba Mihu, Carmen Mihaela Healthcare (Basel) Article Pathological analysis of ovarian cysts shows specific fluid characteristics that cannot be standardly evaluated on computer tomography (CT) examinations. This study aimed to assess the ovarian cysts’ fluid attenuation values on the native (Np), arterial (Ap), and venous (Vp) contrast phases of seventy patients with ovarian cysts who underwent CT examinations and were retrospectively included in this study. Patients were divided according to their final diagnosis into the benign group (n = 32) and malignant group (n = 38; of which 27 were primary and 11 were secondary lesions). Two radiologists measured the fluid attenuation values on each contrast phase, and the average values were used to discriminate between benign and malignant groups and primary tumors and metastases via univariate, multivariate, multiple regression, and receiver operating characteristics analyses. The Ap densities (p = 0.0002) were independently associated with malignant cysts. Based on the densities measured on all three phases, neoplastic lesions could be diagnosed with 89.47% sensitivity and 62.5% specificity. The Np densities (p = 0.0005) were able to identify metastases with 90.91% sensitivity and 70.37% specificity, while the combined densities of all three phases diagnosed secondary lesions with 72.73% sensitivity and 92.59% specificity. The ovarian cysts’ fluid densities could function as an adjuvant criterion to the classic CT evaluation of ovarian cysts. MDPI 2020-10-14 /pmc/articles/PMC7711840/ /pubmed/33066370 http://dx.doi.org/10.3390/healthcare8040398 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lupean, Roxana-Adelina
Ștefan, Paul-Andrei
Oancea, Mihaela Daniela
Măluțan, Andrei Mihai
Lebovici, Andrei
Pușcaș, Marius Emil
Csutak, Csaba
Mihu, Carmen Mihaela
Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values
title Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values
title_full Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values
title_fullStr Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values
title_full_unstemmed Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values
title_short Computer Tomography in the Diagnosis of Ovarian Cysts: The Role of Fluid Attenuation Values
title_sort computer tomography in the diagnosis of ovarian cysts: the role of fluid attenuation values
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711840/
https://www.ncbi.nlm.nih.gov/pubmed/33066370
http://dx.doi.org/10.3390/healthcare8040398
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