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Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development

Peroxisomes and mitochondria are organelles that perform major functions in the cell and whose activity is very closely associated. In fungi, the function of these organelles is critical for many developmental processes. Recent studies have disclosed that, additionally, fungal development comprises...

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Autores principales: Navarro-Espíndola, Raful, Suaste-Olmos, Fernando, Peraza-Reyes, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711908/
https://www.ncbi.nlm.nih.gov/pubmed/33233491
http://dx.doi.org/10.3390/jof6040302
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author Navarro-Espíndola, Raful
Suaste-Olmos, Fernando
Peraza-Reyes, Leonardo
author_facet Navarro-Espíndola, Raful
Suaste-Olmos, Fernando
Peraza-Reyes, Leonardo
author_sort Navarro-Espíndola, Raful
collection PubMed
description Peroxisomes and mitochondria are organelles that perform major functions in the cell and whose activity is very closely associated. In fungi, the function of these organelles is critical for many developmental processes. Recent studies have disclosed that, additionally, fungal development comprises a dynamic regulation of the activity of these organelles, which involves a developmental regulation of organelle assembly, as well as a dynamic modulation of the abundance, distribution, and morphology of these organelles. Furthermore, for many of these processes, the dynamics of peroxisomes and mitochondria are governed by common factors. Notably, intense research has revealed that the process that drives the division of mitochondria and peroxisomes contributes to several developmental processes—including the formation of asexual spores, the differentiation of infective structures by pathogenic fungi, and sexual development—and that these processes rely on selective removal of these organelles via autophagy. Furthermore, evidence has been obtained suggesting a coordinated regulation of organelle assembly and dynamics during development and supporting the existence of regulatory systems controlling fungal development in response to mitochondrial activity. Gathered information underscores an important role for mitochondrial and peroxisome dynamics in fungal development and suggests that this process involves the concerted activity of these organelles.
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spelling pubmed-77119082020-12-04 Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development Navarro-Espíndola, Raful Suaste-Olmos, Fernando Peraza-Reyes, Leonardo J Fungi (Basel) Review Peroxisomes and mitochondria are organelles that perform major functions in the cell and whose activity is very closely associated. In fungi, the function of these organelles is critical for many developmental processes. Recent studies have disclosed that, additionally, fungal development comprises a dynamic regulation of the activity of these organelles, which involves a developmental regulation of organelle assembly, as well as a dynamic modulation of the abundance, distribution, and morphology of these organelles. Furthermore, for many of these processes, the dynamics of peroxisomes and mitochondria are governed by common factors. Notably, intense research has revealed that the process that drives the division of mitochondria and peroxisomes contributes to several developmental processes—including the formation of asexual spores, the differentiation of infective structures by pathogenic fungi, and sexual development—and that these processes rely on selective removal of these organelles via autophagy. Furthermore, evidence has been obtained suggesting a coordinated regulation of organelle assembly and dynamics during development and supporting the existence of regulatory systems controlling fungal development in response to mitochondrial activity. Gathered information underscores an important role for mitochondrial and peroxisome dynamics in fungal development and suggests that this process involves the concerted activity of these organelles. MDPI 2020-11-20 /pmc/articles/PMC7711908/ /pubmed/33233491 http://dx.doi.org/10.3390/jof6040302 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Navarro-Espíndola, Raful
Suaste-Olmos, Fernando
Peraza-Reyes, Leonardo
Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development
title Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development
title_full Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development
title_fullStr Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development
title_full_unstemmed Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development
title_short Dynamic Regulation of Peroxisomes and Mitochondria during Fungal Development
title_sort dynamic regulation of peroxisomes and mitochondria during fungal development
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711908/
https://www.ncbi.nlm.nih.gov/pubmed/33233491
http://dx.doi.org/10.3390/jof6040302
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