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Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
(1) Aim: The aim of this study was to assess the preferences of oral anticoagulants (OA) in patients diagnosed with deep vein thrombosis (DVT) of lower limbs or non-valvular atrial fibrillation (AF) requiring anticoagulation for medium/long term. (2) Materials and methods: the study included consecu...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711926/ https://www.ncbi.nlm.nih.gov/pubmed/33076509 http://dx.doi.org/10.3390/healthcare8040404 |
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author | Vesa, Ştefan Cristian Vlaicu, Sonia Irina Crișan, Sorin Sabin, Octavia Saraci, George Văcăraș, Vitalie Popa, Daciana Elena Pârcălab, Paula Donca, Valer Ioan Macarie, Antonia Eugenia Sava, Madalina Buzoianu, Anca Dana |
author_facet | Vesa, Ştefan Cristian Vlaicu, Sonia Irina Crișan, Sorin Sabin, Octavia Saraci, George Văcăraș, Vitalie Popa, Daciana Elena Pârcălab, Paula Donca, Valer Ioan Macarie, Antonia Eugenia Sava, Madalina Buzoianu, Anca Dana |
author_sort | Vesa, Ştefan Cristian |
collection | PubMed |
description | (1) Aim: The aim of this study was to assess the preferences of oral anticoagulants (OA) in patients diagnosed with deep vein thrombosis (DVT) of lower limbs or non-valvular atrial fibrillation (AF) requiring anticoagulation for medium/long term. (2) Materials and methods: the study included consecutive patients admitted with a diagnosis of either acute DVT of lower limbs (without signs of pulmonary embolism) or non-valvular AF who required oral anticoagulation, in a time frame of 18 months from January 2017 until June 2018. The following data were recorded: demographic variables, comorbidities (ischemic heart disease, arterial hypertension, heart failure, stroke, peripheral artery disease, diabetes mellitus, obesity), type and dose of OA (acenocoumarol, dabigatran, apixaban, rivaroxaban), complications due to the use of OA. (3) Results: AF patients were older and had considerably more cardiovascular comorbidities than DVT patients. Vitamin K antagonists (VKA) were more likely to be administered in patients with AF, as they had indication for indefinite anticoagulation. VKA were more frequently prescribed in patients with ischemic heart disease, heart failure, and diabetes compared with DVT patients. Moreover, complications related to OA use were more frequent in the VKA group. Almost half of patients with acute DVT (48.5%) were treated with direct OA (DOAC) rather than VKA, and only a quarter of AF patients (24.8%) were treated with DOACs. |
format | Online Article Text |
id | pubmed-7711926 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77119262020-12-04 Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation Vesa, Ştefan Cristian Vlaicu, Sonia Irina Crișan, Sorin Sabin, Octavia Saraci, George Văcăraș, Vitalie Popa, Daciana Elena Pârcălab, Paula Donca, Valer Ioan Macarie, Antonia Eugenia Sava, Madalina Buzoianu, Anca Dana Healthcare (Basel) Article (1) Aim: The aim of this study was to assess the preferences of oral anticoagulants (OA) in patients diagnosed with deep vein thrombosis (DVT) of lower limbs or non-valvular atrial fibrillation (AF) requiring anticoagulation for medium/long term. (2) Materials and methods: the study included consecutive patients admitted with a diagnosis of either acute DVT of lower limbs (without signs of pulmonary embolism) or non-valvular AF who required oral anticoagulation, in a time frame of 18 months from January 2017 until June 2018. The following data were recorded: demographic variables, comorbidities (ischemic heart disease, arterial hypertension, heart failure, stroke, peripheral artery disease, diabetes mellitus, obesity), type and dose of OA (acenocoumarol, dabigatran, apixaban, rivaroxaban), complications due to the use of OA. (3) Results: AF patients were older and had considerably more cardiovascular comorbidities than DVT patients. Vitamin K antagonists (VKA) were more likely to be administered in patients with AF, as they had indication for indefinite anticoagulation. VKA were more frequently prescribed in patients with ischemic heart disease, heart failure, and diabetes compared with DVT patients. Moreover, complications related to OA use were more frequent in the VKA group. Almost half of patients with acute DVT (48.5%) were treated with direct OA (DOAC) rather than VKA, and only a quarter of AF patients (24.8%) were treated with DOACs. MDPI 2020-10-15 /pmc/articles/PMC7711926/ /pubmed/33076509 http://dx.doi.org/10.3390/healthcare8040404 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vesa, Ştefan Cristian Vlaicu, Sonia Irina Crișan, Sorin Sabin, Octavia Saraci, George Văcăraș, Vitalie Popa, Daciana Elena Pârcălab, Paula Donca, Valer Ioan Macarie, Antonia Eugenia Sava, Madalina Buzoianu, Anca Dana Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation |
title | Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation |
title_full | Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation |
title_fullStr | Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation |
title_full_unstemmed | Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation |
title_short | Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation |
title_sort | oral anticoagulants preference in hospitalized patients with acute deep vein thrombosis or non-valvular atrial fibrillation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711926/ https://www.ncbi.nlm.nih.gov/pubmed/33076509 http://dx.doi.org/10.3390/healthcare8040404 |
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