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Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation

(1) Aim: The aim of this study was to assess the preferences of oral anticoagulants (OA) in patients diagnosed with deep vein thrombosis (DVT) of lower limbs or non-valvular atrial fibrillation (AF) requiring anticoagulation for medium/long term. (2) Materials and methods: the study included consecu...

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Autores principales: Vesa, Ştefan Cristian, Vlaicu, Sonia Irina, Crișan, Sorin, Sabin, Octavia, Saraci, George, Văcăraș, Vitalie, Popa, Daciana Elena, Pârcălab, Paula, Donca, Valer Ioan, Macarie, Antonia Eugenia, Sava, Madalina, Buzoianu, Anca Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711926/
https://www.ncbi.nlm.nih.gov/pubmed/33076509
http://dx.doi.org/10.3390/healthcare8040404
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author Vesa, Ştefan Cristian
Vlaicu, Sonia Irina
Crișan, Sorin
Sabin, Octavia
Saraci, George
Văcăraș, Vitalie
Popa, Daciana Elena
Pârcălab, Paula
Donca, Valer Ioan
Macarie, Antonia Eugenia
Sava, Madalina
Buzoianu, Anca Dana
author_facet Vesa, Ştefan Cristian
Vlaicu, Sonia Irina
Crișan, Sorin
Sabin, Octavia
Saraci, George
Văcăraș, Vitalie
Popa, Daciana Elena
Pârcălab, Paula
Donca, Valer Ioan
Macarie, Antonia Eugenia
Sava, Madalina
Buzoianu, Anca Dana
author_sort Vesa, Ştefan Cristian
collection PubMed
description (1) Aim: The aim of this study was to assess the preferences of oral anticoagulants (OA) in patients diagnosed with deep vein thrombosis (DVT) of lower limbs or non-valvular atrial fibrillation (AF) requiring anticoagulation for medium/long term. (2) Materials and methods: the study included consecutive patients admitted with a diagnosis of either acute DVT of lower limbs (without signs of pulmonary embolism) or non-valvular AF who required oral anticoagulation, in a time frame of 18 months from January 2017 until June 2018. The following data were recorded: demographic variables, comorbidities (ischemic heart disease, arterial hypertension, heart failure, stroke, peripheral artery disease, diabetes mellitus, obesity), type and dose of OA (acenocoumarol, dabigatran, apixaban, rivaroxaban), complications due to the use of OA. (3) Results: AF patients were older and had considerably more cardiovascular comorbidities than DVT patients. Vitamin K antagonists (VKA) were more likely to be administered in patients with AF, as they had indication for indefinite anticoagulation. VKA were more frequently prescribed in patients with ischemic heart disease, heart failure, and diabetes compared with DVT patients. Moreover, complications related to OA use were more frequent in the VKA group. Almost half of patients with acute DVT (48.5%) were treated with direct OA (DOAC) rather than VKA, and only a quarter of AF patients (24.8%) were treated with DOACs.
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spelling pubmed-77119262020-12-04 Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation Vesa, Ştefan Cristian Vlaicu, Sonia Irina Crișan, Sorin Sabin, Octavia Saraci, George Văcăraș, Vitalie Popa, Daciana Elena Pârcălab, Paula Donca, Valer Ioan Macarie, Antonia Eugenia Sava, Madalina Buzoianu, Anca Dana Healthcare (Basel) Article (1) Aim: The aim of this study was to assess the preferences of oral anticoagulants (OA) in patients diagnosed with deep vein thrombosis (DVT) of lower limbs or non-valvular atrial fibrillation (AF) requiring anticoagulation for medium/long term. (2) Materials and methods: the study included consecutive patients admitted with a diagnosis of either acute DVT of lower limbs (without signs of pulmonary embolism) or non-valvular AF who required oral anticoagulation, in a time frame of 18 months from January 2017 until June 2018. The following data were recorded: demographic variables, comorbidities (ischemic heart disease, arterial hypertension, heart failure, stroke, peripheral artery disease, diabetes mellitus, obesity), type and dose of OA (acenocoumarol, dabigatran, apixaban, rivaroxaban), complications due to the use of OA. (3) Results: AF patients were older and had considerably more cardiovascular comorbidities than DVT patients. Vitamin K antagonists (VKA) were more likely to be administered in patients with AF, as they had indication for indefinite anticoagulation. VKA were more frequently prescribed in patients with ischemic heart disease, heart failure, and diabetes compared with DVT patients. Moreover, complications related to OA use were more frequent in the VKA group. Almost half of patients with acute DVT (48.5%) were treated with direct OA (DOAC) rather than VKA, and only a quarter of AF patients (24.8%) were treated with DOACs. MDPI 2020-10-15 /pmc/articles/PMC7711926/ /pubmed/33076509 http://dx.doi.org/10.3390/healthcare8040404 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vesa, Ştefan Cristian
Vlaicu, Sonia Irina
Crișan, Sorin
Sabin, Octavia
Saraci, George
Văcăraș, Vitalie
Popa, Daciana Elena
Pârcălab, Paula
Donca, Valer Ioan
Macarie, Antonia Eugenia
Sava, Madalina
Buzoianu, Anca Dana
Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
title Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
title_full Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
title_fullStr Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
title_full_unstemmed Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
title_short Oral Anticoagulants Preference in Hospitalized Patients with Acute Deep Vein Thrombosis or Non-Valvular Atrial Fibrillation
title_sort oral anticoagulants preference in hospitalized patients with acute deep vein thrombosis or non-valvular atrial fibrillation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711926/
https://www.ncbi.nlm.nih.gov/pubmed/33076509
http://dx.doi.org/10.3390/healthcare8040404
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