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Safety profile of the transcription factor EB (TFEB)-based gene therapy through intracranial injection in mice

Transcription factor EB (TFEB)-based gene therapy is a promising therapeutic strategy in treating neurodegenerative diseases by promoting autophagy/lysosome-mediated degradation and clearance of misfolded proteins that contribute to the pathogenesis of these diseases. However, recent findings have s...

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Detalles Bibliográficos
Autores principales:	Li, Zhenyu, Ding, Guangqian, Wang, Yudi, Zheng, Zelong, Lv, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711953/ https://www.ncbi.nlm.nih.gov/pubmed/33335764 http://dx.doi.org/10.1515/tnsci-2020-0132

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