Redefining Non-Inferiority in Anamnestic Antibody Responses Using the Mean Increase of Log-Transformed Antibody Titers after Revaccination: Secondary Analysis of a Randomized Controlled Rabies Vaccination Trial

Non-inferiority in the anamnestic antibody response is conventionally determined by comparing seroconversion rates after revaccination. However, this approach is inadequate in the case of high pre-booster antibody titers. Therefore, we propose an alternative method to determine non-inferiority of bo...

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Detalles Bibliográficos
Autores principales: Overduin, Lisanne A., Soentjens, Patrick H. P., Goeman, Jelle J., Berkowska, Magdalena A., van Dongen, Jacques J. M., Visser, Leo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712065/
https://www.ncbi.nlm.nih.gov/pubmed/33276423
http://dx.doi.org/10.3390/vaccines8040721

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