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Degradomics-Based Analysis of Tetanus Toxoids as a Quality Control Assay
Currently, batch release of toxoid vaccines, such as diphtheria and tetanus toxoid, requires animal tests to confirm safety and immunogenicity. Efforts are being made to replace these tests with in vitro assays in a consistency approach. Limitations of current in vitro assays include the need for re...
Autores principales: | Michiels, Thomas J. M., Tilstra, Wichard, Hamzink, Martin R. J., de Ridder, Justin W., Danial, Maarten, Meiring, Hugo D., Kersten, Gideon F. A., Jiskoot, Wim, Metz, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712181/ https://www.ncbi.nlm.nih.gov/pubmed/33271767 http://dx.doi.org/10.3390/vaccines8040712 |
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