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Safety and Immunogenicity of the GamTBvac, the Recombinant Subunit Tuberculosis Vaccine Candidate: A Phase II, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study

GamTBvac is a candidate tuberculosis vaccine with two fusion proteins, containing Ag85a, ESAT6, CFP10, and a dextran-binding domain (DBD). Phase II of a double-blind, randomized, multicenter, placebo-controlled study in parallel groups in healthy adults to evaluate the safety and immunogenicity of G...

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Detalles Bibliográficos
Autores principales: Tkachuk, Artem P., Bykonia, Evgeniia N., Popova, Liubov I., Kleymenov, Denis A., Semashko, Maria A., Chulanov, Vladimir P., Fitilev, Sergey B., Maksimov, Semyon L., Smolyarchuk, Elena A., Manuylov, Victor A., Vasina, Daria V., Gushchin, Vladimir A., Gintsburg, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712213/
https://www.ncbi.nlm.nih.gov/pubmed/33153191
http://dx.doi.org/10.3390/vaccines8040652