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Safety and Immunogenicity of the GamTBvac, the Recombinant Subunit Tuberculosis Vaccine Candidate: A Phase II, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study
GamTBvac is a candidate tuberculosis vaccine with two fusion proteins, containing Ag85a, ESAT6, CFP10, and a dextran-binding domain (DBD). Phase II of a double-blind, randomized, multicenter, placebo-controlled study in parallel groups in healthy adults to evaluate the safety and immunogenicity of G...
Autores principales: | Tkachuk, Artem P., Bykonia, Evgeniia N., Popova, Liubov I., Kleymenov, Denis A., Semashko, Maria A., Chulanov, Vladimir P., Fitilev, Sergey B., Maksimov, Semyon L., Smolyarchuk, Elena A., Manuylov, Victor A., Vasina, Daria V., Gushchin, Vladimir A., Gintsburg, Alexander L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712213/ https://www.ncbi.nlm.nih.gov/pubmed/33153191 http://dx.doi.org/10.3390/vaccines8040652 |
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