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The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa

Missed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. So...

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Autores principales: Ndwandwe, Duduzile, Nnaji, Chukwudi A., Wiysonge, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712226/
https://www.ncbi.nlm.nih.gov/pubmed/33255767
http://dx.doi.org/10.3390/vaccines8040705
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author Ndwandwe, Duduzile
Nnaji, Chukwudi A.
Wiysonge, Charles S.
author_facet Ndwandwe, Duduzile
Nnaji, Chukwudi A.
Wiysonge, Charles S.
author_sort Ndwandwe, Duduzile
collection PubMed
description Missed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. South Africa is sub-divided into nine administrative provinces. We used nationally representative data from the 2016 South African Demographic and Health Survey. We considered MOV to have occurred if a child aged 12–23 months old had not taken all scheduled basic vaccine doses despite having any of the following contacts with health services: delivery in a health facility; postnatal clinic visit; receipt of vitamin A; and any child-related treatment at a health facility. Multilevel logistic regression was used to determine factors associated with MOV. The national prevalence of MOV among children aged 12–23 months was 40.1%. Children whose mothers attended facility-based antenatal care were considerably less likely to experience MOV than those whose mothers did not attend antenatal care: odds ratio (OR) 0.41, 95% confidence interval (CI) 0.19 to 0.88. Conversely, the independent predictor of an increased MOV among children was residence in either the Gauteng province (OR 2.97, 95% CI 1.29 to 6.81) or Mpumalanga province (OR 2.32, 95%CI 1.04 to 5.18); compared to residence in the Free State province. Our findings suggest a high burden of MOV among children in South Africa and that MOV may be associated with individual and contextual factors. The findings also underscore the need for further exploration of the contextual factors contributing to MOV in South Africa.
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spelling pubmed-77122262020-12-04 The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa Ndwandwe, Duduzile Nnaji, Chukwudi A. Wiysonge, Charles S. Vaccines (Basel) Article Missed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. South Africa is sub-divided into nine administrative provinces. We used nationally representative data from the 2016 South African Demographic and Health Survey. We considered MOV to have occurred if a child aged 12–23 months old had not taken all scheduled basic vaccine doses despite having any of the following contacts with health services: delivery in a health facility; postnatal clinic visit; receipt of vitamin A; and any child-related treatment at a health facility. Multilevel logistic regression was used to determine factors associated with MOV. The national prevalence of MOV among children aged 12–23 months was 40.1%. Children whose mothers attended facility-based antenatal care were considerably less likely to experience MOV than those whose mothers did not attend antenatal care: odds ratio (OR) 0.41, 95% confidence interval (CI) 0.19 to 0.88. Conversely, the independent predictor of an increased MOV among children was residence in either the Gauteng province (OR 2.97, 95% CI 1.29 to 6.81) or Mpumalanga province (OR 2.32, 95%CI 1.04 to 5.18); compared to residence in the Free State province. Our findings suggest a high burden of MOV among children in South Africa and that MOV may be associated with individual and contextual factors. The findings also underscore the need for further exploration of the contextual factors contributing to MOV in South Africa. MDPI 2020-11-25 /pmc/articles/PMC7712226/ /pubmed/33255767 http://dx.doi.org/10.3390/vaccines8040705 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ndwandwe, Duduzile
Nnaji, Chukwudi A.
Wiysonge, Charles S.
The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_full The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_fullStr The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_full_unstemmed The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_short The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_sort magnitude and determinants of missed opportunities for childhood vaccination in south africa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712226/
https://www.ncbi.nlm.nih.gov/pubmed/33255767
http://dx.doi.org/10.3390/vaccines8040705
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