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The “authentic subjective experience” of memory in Alzheimer’s disease

Most research has mainly focused on the decline of the subjective experience in Alzheimer’s disease (AD). However, few attempts have been made to evaluate whether subjective experience may be maintained in AD. In this narrative review, we attempt to provide a positive view, according to which patien...

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Autores principales: El Haj, Mohamad, Moustafa, Ahmed A., Roche, Jean, Pasquier, Florence, Kapogiannis, Dimitrios, Gallouj, Karim, Antoine, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712381/
https://www.ncbi.nlm.nih.gov/pubmed/33335759
http://dx.doi.org/10.1515/tnsci-2020-0123
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author El Haj, Mohamad
Moustafa, Ahmed A.
Roche, Jean
Pasquier, Florence
Kapogiannis, Dimitrios
Gallouj, Karim
Antoine, Pascal
author_facet El Haj, Mohamad
Moustafa, Ahmed A.
Roche, Jean
Pasquier, Florence
Kapogiannis, Dimitrios
Gallouj, Karim
Antoine, Pascal
author_sort El Haj, Mohamad
collection PubMed
description Most research has mainly focused on the decline of the subjective experience in Alzheimer’s disease (AD). However, few attempts have been made to evaluate whether subjective experience may be maintained in AD. In this narrative review, we attempt to provide a positive view, according to which patients with AD can enjoy, to some extent, subjective experience during memory retrieval. Memory and expression difficulties (e.g., aphasia) limit the ability of patients with AD to describe their memories, resulting in a little specificity of reported memories. However, according to the “authentic subjective experience” view, we propose in this study that the ability to mentally relive these memories could be preserved in the patients. By proposing the authentic subjective experience view, we attempt to provide an alternative view to the general consideration that the patients suffer a diminished subjective experience. This view can contribute to a larger clinical framework that gives a positive meaning to the subjective experience of patients with AD. Furthermore, several clinical and empirical implications can be drawn from the authentic subjective experience view, including the possibility to evaluate behavioral correlates of the subjective experience in AD.
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spelling pubmed-77123812020-12-16 The “authentic subjective experience” of memory in Alzheimer’s disease El Haj, Mohamad Moustafa, Ahmed A. Roche, Jean Pasquier, Florence Kapogiannis, Dimitrios Gallouj, Karim Antoine, Pascal Transl Neurosci Mini-Review Most research has mainly focused on the decline of the subjective experience in Alzheimer’s disease (AD). However, few attempts have been made to evaluate whether subjective experience may be maintained in AD. In this narrative review, we attempt to provide a positive view, according to which patients with AD can enjoy, to some extent, subjective experience during memory retrieval. Memory and expression difficulties (e.g., aphasia) limit the ability of patients with AD to describe their memories, resulting in a little specificity of reported memories. However, according to the “authentic subjective experience” view, we propose in this study that the ability to mentally relive these memories could be preserved in the patients. By proposing the authentic subjective experience view, we attempt to provide an alternative view to the general consideration that the patients suffer a diminished subjective experience. This view can contribute to a larger clinical framework that gives a positive meaning to the subjective experience of patients with AD. Furthermore, several clinical and empirical implications can be drawn from the authentic subjective experience view, including the possibility to evaluate behavioral correlates of the subjective experience in AD. De Gruyter 2020-06-03 /pmc/articles/PMC7712381/ /pubmed/33335759 http://dx.doi.org/10.1515/tnsci-2020-0123 Text en © 2020 Mohamad El Haj et al., published by De Gruyter http://creativecommons.org/licenses/by/4.0 This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Mini-Review
El Haj, Mohamad
Moustafa, Ahmed A.
Roche, Jean
Pasquier, Florence
Kapogiannis, Dimitrios
Gallouj, Karim
Antoine, Pascal
The “authentic subjective experience” of memory in Alzheimer’s disease
title The “authentic subjective experience” of memory in Alzheimer’s disease
title_full The “authentic subjective experience” of memory in Alzheimer’s disease
title_fullStr The “authentic subjective experience” of memory in Alzheimer’s disease
title_full_unstemmed The “authentic subjective experience” of memory in Alzheimer’s disease
title_short The “authentic subjective experience” of memory in Alzheimer’s disease
title_sort “authentic subjective experience” of memory in alzheimer’s disease
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712381/
https://www.ncbi.nlm.nih.gov/pubmed/33335759
http://dx.doi.org/10.1515/tnsci-2020-0123
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