Cargando…
Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients
We aimed to investigate the prevalence of sarcopenia using new diagnostic criteria and association of sarcopenia with cardiopulmonary function and physical activity (PA) in preoperative lung cancer patients. The data of 614 patients were obtained from the CATCH-LUNG cohort study. Patients were class...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712435/ https://www.ncbi.nlm.nih.gov/pubmed/33066134 http://dx.doi.org/10.3390/jpm10040166 |
_version_ | 1783618374738116608 |
---|---|
author | Kong, Sunga Shin, Sumin Lee, Jae Kyung Lee, Genehee Kang, Danbee Cho, Juhee Kim, Hong Kwan Zo, Jae Ill Shim, Young Mog Park, Hye Yun Shin, Dong Wook |
author_facet | Kong, Sunga Shin, Sumin Lee, Jae Kyung Lee, Genehee Kang, Danbee Cho, Juhee Kim, Hong Kwan Zo, Jae Ill Shim, Young Mog Park, Hye Yun Shin, Dong Wook |
author_sort | Kong, Sunga |
collection | PubMed |
description | We aimed to investigate the prevalence of sarcopenia using new diagnostic criteria and association of sarcopenia with cardiopulmonary function and physical activity (PA) in preoperative lung cancer patients. The data of 614 patients were obtained from the CATCH-LUNG cohort study. Patients were classified into three groups—normal (n = 520), pre-sarcopenia (n = 60, low skeletal muscle mass index only), and sarcopenia (n = 34, low SMI and strength). Cardiopulmonary function was measured using the 6-min walk test (6MWT), and PA was objectively measured using a wearable device. The adjusted odds ratio (aOR) for a <400-m distance in 6MWT was 3.52 (95% confidence interval (CI) 1.34–9.21) and 6.63 (95% CI 2.25–19.60) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group. The aOR (95% CI) for <5000 steps/day was 1.64 (0.65–4.16) and 4.20 (1.55–11.38) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group. In conclusion, the prevalence of pre-sarcopenia and sarcopenia was 9.8% and 5.5%, respectively, among preoperative lung cancer patients. Cardiopulmonary function and physical activity were significantly lower in the pre-sarcopenia and sarcopenia groups than in the normal group. Patients with sarcopenia had more robust findings, suggesting the importance of muscle strength and mass. |
format | Online Article Text |
id | pubmed-7712435 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77124352020-12-04 Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients Kong, Sunga Shin, Sumin Lee, Jae Kyung Lee, Genehee Kang, Danbee Cho, Juhee Kim, Hong Kwan Zo, Jae Ill Shim, Young Mog Park, Hye Yun Shin, Dong Wook J Pers Med Article We aimed to investigate the prevalence of sarcopenia using new diagnostic criteria and association of sarcopenia with cardiopulmonary function and physical activity (PA) in preoperative lung cancer patients. The data of 614 patients were obtained from the CATCH-LUNG cohort study. Patients were classified into three groups—normal (n = 520), pre-sarcopenia (n = 60, low skeletal muscle mass index only), and sarcopenia (n = 34, low SMI and strength). Cardiopulmonary function was measured using the 6-min walk test (6MWT), and PA was objectively measured using a wearable device. The adjusted odds ratio (aOR) for a <400-m distance in 6MWT was 3.52 (95% confidence interval (CI) 1.34–9.21) and 6.63 (95% CI 2.25–19.60) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group. The aOR (95% CI) for <5000 steps/day was 1.64 (0.65–4.16) and 4.20 (1.55–11.38) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group. In conclusion, the prevalence of pre-sarcopenia and sarcopenia was 9.8% and 5.5%, respectively, among preoperative lung cancer patients. Cardiopulmonary function and physical activity were significantly lower in the pre-sarcopenia and sarcopenia groups than in the normal group. Patients with sarcopenia had more robust findings, suggesting the importance of muscle strength and mass. MDPI 2020-10-13 /pmc/articles/PMC7712435/ /pubmed/33066134 http://dx.doi.org/10.3390/jpm10040166 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kong, Sunga Shin, Sumin Lee, Jae Kyung Lee, Genehee Kang, Danbee Cho, Juhee Kim, Hong Kwan Zo, Jae Ill Shim, Young Mog Park, Hye Yun Shin, Dong Wook Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients |
title | Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients |
title_full | Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients |
title_fullStr | Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients |
title_full_unstemmed | Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients |
title_short | Association between Sarcopenia and Physical Function among Preoperative Lung Cancer Patients |
title_sort | association between sarcopenia and physical function among preoperative lung cancer patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712435/ https://www.ncbi.nlm.nih.gov/pubmed/33066134 http://dx.doi.org/10.3390/jpm10040166 |
work_keys_str_mv | AT kongsunga associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT shinsumin associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT leejaekyung associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT leegenehee associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT kangdanbee associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT chojuhee associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT kimhongkwan associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT zojaeill associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT shimyoungmog associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT parkhyeyun associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients AT shindongwook associationbetweensarcopeniaandphysicalfunctionamongpreoperativelungcancerpatients |