Cargando…

Programmable N6-methyladenosine modification of CDCP1 mRNA by RCas9-methyltransferase like 3 conjugates promotes bladder cancer development

Accumulating evidence has revealed significant roles for N6-methyladenosine (m 6 A) modification in the development of various cancers. We previously demonstrated an oncogenic role of m 6 A-modified CUB domain containing protein 1 (CDCP1) in bladder cancer (BC) progression. However, the biological f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ying, Xiaoling, Jiang, Xu, Zhang, Haiqing, Liu, Bixia, Huang, Yapeng, Zhu, Xiaowei, Qi, Defeng, Yuan, Gang, Luo, Junhang, Ji, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712571/ https://www.ncbi.nlm.nih.gov/pubmed/33267838 http://dx.doi.org/10.1186/s12943-020-01289-0

Ejemplares similares

N(6)-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer
por: Jin, Huan, et al.
Publicado: (2019)

METTL1‐m(7)G‐EGFR/EFEMP1 axis promotes the bladder cancer development
por: Ying, Xiaoling, et al.
Publicado: (2021)

Dynamic m(6)A mRNA methylation reveals the role of METTL3-m(6)A-CDCP1 signaling axis in chemical carcinogenesis
por: Yang, Fan, et al.
Publicado: (2019)

Expression of RCAS1 Correlates with Urothelial Bladder Cancer Malignancy
por: Jóźwicki, Wojciech, et al.
Publicado: (2015)

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer
por: Harrington, Brittney S., et al.
Publicado: (2020)

Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase
por: Xia, Zhen, et al.
Publicado: (2021)

The placental RCAS1 expression during stillbirth
por: Wicherek, Lukasz, et al.
Publicado: (2005)

Programmable RNA N(6)-methyladenosine editing by CRISPR-Cas9 conjugates
por: Liu, Xiao-Min, et al.
Publicado: (2019)

The role of RNA N(6)-methyladenosine methyltransferase in cancers
por: Huang, Jiali, et al.
Publicado: (2021)

N6-methyladenosine methyltransferases: functions, regulation, and clinical potential
por: Huang, Wei, et al.
Publicado: (2021)

The human methyltransferase ZCCHC4 catalyses N(6)-methyladenosine modification of 28S ribosomal RNA
por: Pinto, Rita, et al.
Publicado: (2020)

RCAS-RNAi: A loss-of-function method for the developing chick retina
por: Harpavat, Sanjiv, et al.
Publicado: (2006)

RCAS: an RNA centric annotation system for transcriptome-wide regions of interest
por: Uyar, Bora, et al.
Publicado: (2017)

Transcultural adaptation of the revised caregiving appraisal scale (RCAS) in the Spanish population
por: Cueli Arce, Monica, et al.
Publicado: (2022)

New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA
por: Kempenaers, Morgane, et al.
Publicado: (2010)

The m6A Methyltransferase METTL14-Mediated N6-Methyladenosine Modification of PTEN mRNA Inhibits Tumor Growth and Metastasis in Stomach Adenocarcinoma
por: Yao, Qi, et al.
Publicado: (2021)

The m6A Methyltransferase METTL3-Mediated N6-Methyladenosine Modification of DEK mRNA to Promote Gastric Cancer Cell Growth and Metastasis
por: Zhang, Hui-Min, et al.
Publicado: (2022)

hsa_circ_0005358 suppresses cervical cancer metastasis by interacting with PTBP1 protein to destabilize CDCP1 mRNA
por: Cen, Yixuan, et al.
Publicado: (2021)

Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer
por: Yang, Lifang, et al.
Publicado: (2015)

Identification of CD318 (CDCP1) as novel prognostic marker in AML
por: Heitmann, Jonas S., et al.
Publicado: (2020)

Association between RCAS1 expression and clinical outcome in uterine endometrial cancer
por: Sonoda, K, et al.
Publicado: (2003)

RCAS1 expression in mobile tongue squamous cell carcinoma: An immunohistochemical study
por: Theocharis, Stamatios, et al.
Publicado: (2011)

Multiparametric Longitudinal Profiling of RCAS-tva-Induced PDGFB-Driven Experimental Glioma
por: Becker, Hannes, et al.
Publicado: (2022)

Current Advances in N6-Methyladenosine Methylation Modification During Bladder Cancer
por: Liu, Qiang
Publicado: (2022)

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
por: Ping, Xiao-Li, et al.
Publicado: (2014)

CDCP1 promotes compensatory renal growth by integrating Src and Met signaling
por: Kajiwara, Kentaro, et al.
Publicado: (2021)

Preclinical Molecular PET-CT Imaging Targeting CDCP1 in Colorectal Cancer
por: Cuda, Tahleesa J., et al.
Publicado: (2021)

Cleaved CDCP1 marks the spot: a neoepitope for RAS-driven cancers
por: Donahue, Katelyn L., et al.
Publicado: (2022)

N(6)-Methyladenosine mRNA Modification: From Modification Site Selectivity to Neurological Functions
por: Zhang, Zeyu, et al.
Publicado: (2023)

Apoptotic function of tumor-associated antigen RCAS1 in oral squamous cell carcinoma
por: Tanaka, Hideaki, et al.
Publicado: (2014)

Regaining Confidence after Stroke (RCAS): a feasibility randomised controlled trial (RCT)
por: Horne, Jane C., et al.
Publicado: (2019)

Sequence-specific m(6)A demethylation in RNA by FTO fused to RCas9
por: Rau, Kristina, et al.
Publicado: (2019)

CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy
por: Khan, Tashbib, et al.
Publicado: (2022)

The METTL5-TRMT112 N(6)-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation
por: Sepich-Poore, Caraline, et al.
Publicado: (2022)

Methyltransferase‐like 3 promotes cervical cancer metastasis by enhancing cathepsin L mRNA stability in an N6‐methyladenosine‐dependent manner
por: Liu, Pingping, et al.
Publicado: (2023)

FIONA1 is an RNA N(6)-methyladenosine methyltransferase affecting Arabidopsis photomorphogenesis and flowering
por: Wang, Chunling, et al.
Publicado: (2022)

RNA N6‑methyladenosine methyltransferase WTAP promotes the differentiation of endothelial progenitor cells
por: Wu, Longyun, et al.
Publicado: (2023)

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma
por: Kryza, Thomas, et al.
Publicado: (2020)

Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma
por: Lin, Zhiying, et al.
Publicado: (2022)

AXL/CDCP1/SRC axis confers acquired resistance to osimertinib in lung cancer
por: Murakami, Yuichi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kshpiqf188bpmp5gfen69kl1h8