Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver

We report the first case of non-dermatophytic onychomycosis of the toenail described in Kazakhstan caused by Candida parapsilosis. The biological properties of the strain were studied. C. parapsilosis forms white creamy colonies, smooth with focal wrinkles, and the reversum is light-yellow. The cult...

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Autores principales: Kukhar, Yelena, Smagulova, Ainura, Daniyarova, Ainash, Baiduissenova, Aliya, Kiyan, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712765/
https://www.ncbi.nlm.nih.gov/pubmed/33255642
http://dx.doi.org/10.3390/jof6040313
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author Kukhar, Yelena
Smagulova, Ainura
Daniyarova, Ainash
Baiduissenova, Aliya
Kiyan, Vladimir
author_facet Kukhar, Yelena
Smagulova, Ainura
Daniyarova, Ainash
Baiduissenova, Aliya
Kiyan, Vladimir
author_sort Kukhar, Yelena
collection PubMed
description We report the first case of non-dermatophytic onychomycosis of the toenail described in Kazakhstan caused by Candida parapsilosis. The biological properties of the strain were studied. C. parapsilosis forms white creamy colonies, smooth with focal wrinkles, and the reversum is light-yellow. The culture of C. parapsilosis is represented by a yeast form, characterized by the presence of round or cylindrical yeast cells with active budding. The strain has a high saccharolytic and urease activity and is indifferent to the sucrose and maltose. The C. parapsilosis strain was sensitive to polyene and azole antifungal agents. The highest sensitivity was found to ketoconazole, itraconazole and nystatin.
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spelling pubmed-77127652020-12-04 Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver Kukhar, Yelena Smagulova, Ainura Daniyarova, Ainash Baiduissenova, Aliya Kiyan, Vladimir J Fungi (Basel) Case Report We report the first case of non-dermatophytic onychomycosis of the toenail described in Kazakhstan caused by Candida parapsilosis. The biological properties of the strain were studied. C. parapsilosis forms white creamy colonies, smooth with focal wrinkles, and the reversum is light-yellow. The culture of C. parapsilosis is represented by a yeast form, characterized by the presence of round or cylindrical yeast cells with active budding. The strain has a high saccharolytic and urease activity and is indifferent to the sucrose and maltose. The C. parapsilosis strain was sensitive to polyene and azole antifungal agents. The highest sensitivity was found to ketoconazole, itraconazole and nystatin. MDPI 2020-11-25 /pmc/articles/PMC7712765/ /pubmed/33255642 http://dx.doi.org/10.3390/jof6040313 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kukhar, Yelena
Smagulova, Ainura
Daniyarova, Ainash
Baiduissenova, Aliya
Kiyan, Vladimir
Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver
title Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver
title_full Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver
title_fullStr Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver
title_full_unstemmed Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver
title_short Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver
title_sort candida parapsilosis as a causative agent of onychomycosis in patient with cirrhosis of the liver
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712765/
https://www.ncbi.nlm.nih.gov/pubmed/33255642
http://dx.doi.org/10.3390/jof6040313
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