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Development of a Larval Zebrafish Model for Acute Organophosphorus Nerve Agent and Pesticide Exposure and Therapeutic Evaluation

Organophosphorus compound exposure remains a present threat through agricultural accidents, warfare, or terrorist activity. The primary mechanism of organophosphorus toxicity is through inhibition of the enzyme acetylcholinesterase, with current emergency treatment including anticholinergics, benzod...

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Detalles Bibliográficos
Autores principales: Koenig, Jeffrey A., Acon Chen, Cindy, Shih, Tsung-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712847/
https://www.ncbi.nlm.nih.gov/pubmed/33213094
http://dx.doi.org/10.3390/toxics8040106