Quantification and epigenetic evaluation of the residual pool of hepatitis B covalently closed circular DNA in long-term nucleoside analogue-treated patients

Hepatitis B virus (HBV) covalently closed circular (ccc)DNA is the key genomic form responsible for viral persistence and virological relapse after treatment withdrawal. The assessment of residual intrahepatic cccDNA levels and activity after long-term nucleos(t)ide analogues therapy still represent...

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Detalles Bibliográficos
Autores principales: Lebossé, Fanny, Inchauspé, Aurore, Locatelli, Maëlle, Miaglia, Clothilde, Diederichs, Audrey, Fresquet, Judith, Chapus, Fleur, Hamed, Kamal, Testoni, Barbara, Zoulim, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712874/
https://www.ncbi.nlm.nih.gov/pubmed/33273565
http://dx.doi.org/10.1038/s41598-020-78001-1

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