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Time dynamics of COVID-19

We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming per...

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Detalles Bibliográficos
Autores principales: Carroll, Cody, Bhattacharjee, Satarupa, Chen, Yaqing, Dubey, Paromita, Fan, Jianing, Gajardo, Álvaro, Zhou, Xiner, Müller, Hans-Georg, Wang, Jane-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712909/
https://www.ncbi.nlm.nih.gov/pubmed/33273598
http://dx.doi.org/10.1038/s41598-020-77709-4
Descripción
Sumario:We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming period” largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern.