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Time dynamics of COVID-19

We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming per...

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Autores principales: Carroll, Cody, Bhattacharjee, Satarupa, Chen, Yaqing, Dubey, Paromita, Fan, Jianing, Gajardo, Álvaro, Zhou, Xiner, Müller, Hans-Georg, Wang, Jane-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712909/
https://www.ncbi.nlm.nih.gov/pubmed/33273598
http://dx.doi.org/10.1038/s41598-020-77709-4
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author Carroll, Cody
Bhattacharjee, Satarupa
Chen, Yaqing
Dubey, Paromita
Fan, Jianing
Gajardo, Álvaro
Zhou, Xiner
Müller, Hans-Georg
Wang, Jane-Ling
author_facet Carroll, Cody
Bhattacharjee, Satarupa
Chen, Yaqing
Dubey, Paromita
Fan, Jianing
Gajardo, Álvaro
Zhou, Xiner
Müller, Hans-Georg
Wang, Jane-Ling
author_sort Carroll, Cody
collection PubMed
description We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming period” largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern.
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spelling pubmed-77129092020-12-03 Time dynamics of COVID-19 Carroll, Cody Bhattacharjee, Satarupa Chen, Yaqing Dubey, Paromita Fan, Jianing Gajardo, Álvaro Zhou, Xiner Müller, Hans-Georg Wang, Jane-Ling Sci Rep Article We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming period” largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern. Nature Publishing Group UK 2020-12-03 /pmc/articles/PMC7712909/ /pubmed/33273598 http://dx.doi.org/10.1038/s41598-020-77709-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Carroll, Cody
Bhattacharjee, Satarupa
Chen, Yaqing
Dubey, Paromita
Fan, Jianing
Gajardo, Álvaro
Zhou, Xiner
Müller, Hans-Georg
Wang, Jane-Ling
Time dynamics of COVID-19
title Time dynamics of COVID-19
title_full Time dynamics of COVID-19
title_fullStr Time dynamics of COVID-19
title_full_unstemmed Time dynamics of COVID-19
title_short Time dynamics of COVID-19
title_sort time dynamics of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712909/
https://www.ncbi.nlm.nih.gov/pubmed/33273598
http://dx.doi.org/10.1038/s41598-020-77709-4
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