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Time dynamics of COVID-19
We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming per...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712909/ https://www.ncbi.nlm.nih.gov/pubmed/33273598 http://dx.doi.org/10.1038/s41598-020-77709-4 |
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author | Carroll, Cody Bhattacharjee, Satarupa Chen, Yaqing Dubey, Paromita Fan, Jianing Gajardo, Álvaro Zhou, Xiner Müller, Hans-Georg Wang, Jane-Ling |
author_facet | Carroll, Cody Bhattacharjee, Satarupa Chen, Yaqing Dubey, Paromita Fan, Jianing Gajardo, Álvaro Zhou, Xiner Müller, Hans-Georg Wang, Jane-Ling |
author_sort | Carroll, Cody |
collection | PubMed |
description | We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming period” largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern. |
format | Online Article Text |
id | pubmed-7712909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-77129092020-12-03 Time dynamics of COVID-19 Carroll, Cody Bhattacharjee, Satarupa Chen, Yaqing Dubey, Paromita Fan, Jianing Gajardo, Álvaro Zhou, Xiner Müller, Hans-Georg Wang, Jane-Ling Sci Rep Article We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country’s trajectory during an initial first month “priming period” largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern. Nature Publishing Group UK 2020-12-03 /pmc/articles/PMC7712909/ /pubmed/33273598 http://dx.doi.org/10.1038/s41598-020-77709-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Carroll, Cody Bhattacharjee, Satarupa Chen, Yaqing Dubey, Paromita Fan, Jianing Gajardo, Álvaro Zhou, Xiner Müller, Hans-Georg Wang, Jane-Ling Time dynamics of COVID-19 |
title | Time dynamics of COVID-19 |
title_full | Time dynamics of COVID-19 |
title_fullStr | Time dynamics of COVID-19 |
title_full_unstemmed | Time dynamics of COVID-19 |
title_short | Time dynamics of COVID-19 |
title_sort | time dynamics of covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712909/ https://www.ncbi.nlm.nih.gov/pubmed/33273598 http://dx.doi.org/10.1038/s41598-020-77709-4 |
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