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Solid-state NMR investigation of the involvement of the P2 region in tau amyloid fibrils
The aggregation of hyperphosphorylated tau into amyloid fibrils is closely linked to the progression of Alzheimer’s disease. To gain insight into the link between amyloid structure and disease, the three-dimensional structure of tau fibrils has been studied using solid-state NMR (ssNMR) and cryogeni...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712923/ https://www.ncbi.nlm.nih.gov/pubmed/33273615 http://dx.doi.org/10.1038/s41598-020-78161-0 |