Cargando…

Characterization of Functional Human Skeletal Myotubes and Neuromuscular Junction Derived—From the Same Induced Pluripotent Stem Cell Source

In vitro generation of functional neuromuscular junctions (NMJs) utilizing the same induced pluripotent stem cell (iPSC) source for muscle and motoneurons would be of great value for disease modeling and tissue engineering. Although, differentiation and characterization of iPSC-derived motoneurons a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Xiufang, Badu-Mensah, Agnes, Thomas, Michael C., McAleer, Christopher W., Hickman, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712960/ https://www.ncbi.nlm.nih.gov/pubmed/33105732 http://dx.doi.org/10.3390/bioengineering7040133

Ejemplares similares

Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression
por: Badu-Mensah, Agnes, et al.
Publicado: (2020)

ALS Skeletal Muscle: Victim or Culprit
por: Badu-Mensah, Agnes, et al.
Publicado: (2021)

Hyperglycemia Negatively Affects IPSC-Derived Myoblast Proliferation and Skeletal Muscle Regeneration and Function
por: Badu-Mensah, Agnes, et al.
Publicado: (2022)

The Effect of Skeletal Muscle-Specific Creatine Treatment on ALS NMJ Integrity and Function
por: Badu-Mensah, Agnes, et al.
Publicado: (2023)

Enhanced Development of Skeletal Myotubes from Porcine Induced Pluripotent Stem Cells
por: Genovese, Nicholas J., et al.
Publicado: (2017)

Unlocking the Complexity of Neuromuscular Diseases: Insights from Human Pluripotent Stem Cell-Derived Neuromuscular Junctions
por: Gazzola, Morgan, et al.
Publicado: (2023)

Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines
por: Puttonen, Katja A., et al.
Publicado: (2015)

Creating stem cell‐derived neuromuscular junctions in vitro
por: Luttrell, Shawn M., et al.
Publicado: (2021)

Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes
por: Selvaraj, Sridhar, et al.
Publicado: (2019)

Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions
por: Liu, Wenxuan, et al.
Publicado: (2015)

Inhibition of the Combinatorial Signaling of Transforming Growth Factor-Beta and NOTCH Promotes Myotube Formation of Human Pluripotent Stem Cell-Derived Skeletal Muscle Progenitor Cells
por: Choi, In Young, et al.
Publicado: (2021)

Effect of Denervation on XBP1 in Skeletal Muscle and the Neuromuscular Junction
por: Walter, Lisa A., et al.
Publicado: (2021)

Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration
por: Liu, Wenxuan, et al.
Publicado: (2017)

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle
por: Holt, Ian, et al.
Publicado: (2019)

Contractile Activity of Myotubes Derived from Human Induced Pluripotent Stem Cells: A Model of Duchenne Muscular Dystrophy
por: Yoshioka, Kantaro, et al.
Publicado: (2021)

A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes
por: Swartz, Elliot W., et al.
Publicado: (2016)

Functional Neuromuscular Junctions Formed by Embryonic Stem Cell-Derived Motor Neurons
por: Umbach, Joy A., et al.
Publicado: (2012)

Skeletal muscle mTORC1 regulates neuromuscular junction stability
por: Baraldo, Martina, et al.
Publicado: (2019)

3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures
por: Harley, Peter, et al.
Publicado: (2023)

THE ULTRASTRUCTURE OF THE NEUROMUSCULAR JUNCTIONS OF MAMMALIAN RED, WHITE, AND INTERMEDIATE SKELETAL MUSCLE FIBERS
por: Padykula, Helen A., et al.
Publicado: (1970)

Morphological and functional remodeling of the neuromuscular junction by skeletal muscle PGC-1α
por: Arnold, Anne-Sophie, et al.
Publicado: (2014)

Effects of Nandrolone Decanoate on Skeletal Muscle and Neuromuscular Junction of Sedentary and Exercised Rats
por: Tibúrcio, Felipe Cantore, et al.
Publicado: (2023)

Differential effects of spinal motor neuron-derived and skeletal muscle-derived Rspo2 on acetylcholine receptor clustering at the neuromuscular junction
por: Li, Jin, et al.
Publicado: (2018)

Mature Myotubes Generated From Human-Induced Pluripotent Stem Cells Without Forced Gene Expression
por: Fujiwara, Kei, et al.
Publicado: (2022)

The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease
por: Iyer, Shama R., et al.
Publicado: (2021)

Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing
por: Nimbalkar, Siddharth, et al.
Publicado: (2023)

Skeletal myotube-derived extracellular vesicles enhance itaconate production and attenuate inflammatory responses of macrophages
por: Yamaguchi, Atomu, et al.
Publicado: (2023)

TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling
por: Tang, Yan, et al.
Publicado: (2022)

Prolonged Culture of Aligned Skeletal Myotubes on Micromolded Gelatin Hydrogels
por: Bettadapur, Archana, et al.
Publicado: (2016)

A history of cancer and its treatment: Presidential Address to the Ulster Medical Society. 7th October 2021
por: McAleer, Seamus
Publicado: (2022)

Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas
por: Pappas, Matthew P., et al.
Publicado: (2022)

Reconstruction of the neuromuscular junction connectome
por: Srinivasan, Ranga, et al.
Publicado: (2010)

Axons Compete for Neuromuscular Junctions
por: Robinson, Richard
Publicado: (2012)

Autoimmune Channelopathies at Neuromuscular Junction
por: Huang, Kun, et al.
Publicado: (2019)

Myosin VI in skeletal muscle: its localization in the sarcoplasmic reticulum, neuromuscular junction and muscle nuclei
por: Karolczak, Justyna, et al.
Publicado: (2012)

Atrial Septal Defect, Neuromuscular Junction and Skeletal Abnormalities in Spinal Muscular Atrophy Type III
por: Luan, Xing-Hua, et al.
Publicado: (2017)

Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle
por: Redman, Robert R., et al.
Publicado: (2022)

Purified lectin from skeletal muscle inhibits myotube formation in vitro
Publicado: (1980)

Skeletal myotube formation enhanced by electrospun polyurethane carbon nanotube scaffolds
por: Sirivisoot, Sirinrath, et al.
Publicado: (2011)

Obesity and the microbiome in atopic dermatitis: Therapeutic implications for PPAR-γ agonists
por: McAleer, Jeremy P.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0tceh9q4hi2qhdvt5nfh0p7qmt