Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development

BACKGROUND: Cancer results from the accumulation of mutations leading to the acquisition of cancer promoting characteristics such as increased proliferation and resistance to cell death. In colorectal cancer, an early mutation leading to such features usually occurs in the APC or CTNNB1 genes, there...

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Detalles Bibliográficos
Autores principales: Adam, Ronja S., van Neerven, Sanne M., Pleguezuelos-Manzano, Cayetano, Simmini, Salvatore, Léveillé, Nicolas, de Groot, Nina E., Holding, Andrew N., Markowetz, Florian, Vermeulen, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713000/
https://www.ncbi.nlm.nih.gov/pubmed/33292279
http://dx.doi.org/10.1186/s12935-020-01661-6

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