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Crystal structure of the yeast heterodimeric ADAT2/3 deaminase

BACKGROUND: The adenosine-to-inosine (A-to-I) editing in anticodons of tRNAs is critical for wobble base-pairing during translation. This modification is produced via deamination on A34 and catalyzed by the adenosine deaminase acting on tRNA (ADAT) enzyme. Eukaryotic ADATs are heterodimers composed...

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Detalles Bibliográficos
Autores principales:	Liu, Xiwen, Chen, Ruoyu, Sun, Yujie, Chen, Ran, Zhou, Jie, Tian, Qingnan, Tao, Xuan, Zhang, Zhang, Luo, Guan-zheng, Xie, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713142/ https://www.ncbi.nlm.nih.gov/pubmed/33272269 http://dx.doi.org/10.1186/s12915-020-00920-2

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