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SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1

BACKGROUND: Cancer stem cells (CSCs) have been recognized as an important drug target, however, the underlying mechanisms have not been fully understood. SKP1 is a traditional drug target for cancer therapy, while, whether SKP1 promotes colorectal cancer (CRC) stem cells (CRC-SCs) and the underlying...

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Detalles Bibliográficos
Autores principales:	Tian, Cong, Lang, Tingyuan, Qiu, Jiangfeng, Han, Kun, Zhou, Lei, Min, Daliu, Zhang, Zhiqi, Qi, Dachuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713163/ https://www.ncbi.nlm.nih.gov/pubmed/33292299 http://dx.doi.org/10.1186/s12935-020-01683-0

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