Cargando…
Algorithms for ribosome traffic engineering and their potential in improving host cells' titer and growth rate
mRNA translation is a fundamental cellular process consuming most of the intracellular energy; thus, it is under extensive evolutionary selection for optimization, and its efficiency can affect the host's growth rate. We describe a generic approach for improving the growth rate (fitness) of any...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713304/ https://www.ncbi.nlm.nih.gov/pubmed/33273552 http://dx.doi.org/10.1038/s41598-020-78260-y |