Modelling genetic mosaicism of neurodevelopmental disorders in vivo by a Cre-amplifying fluorescent reporter

Genetic mosaicism, a condition in which an organ includes cells with different genotypes, is frequently present in monogenic diseases of the central nervous system caused by the random inactivation of the X-chromosome, in the case of X-linked pathologies, or by somatic mutations affecting a subset o...

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Detalles Bibliográficos
Autores principales: Trovato, Francesco, Parra, Riccardo, Pracucci, Enrico, Landi, Silvia, Cozzolino, Olga, Nardi, Gabriele, Cruciani, Federica, Pillai, Vinoshene, Mosti, Laura, Cwetsch, Andrzej W., Cancedda, Laura, Gritti, Laura, Sala, Carlo, Verpelli, Chiara, Maset, Andrea, Lodovichi, Claudia, Ratto, Gian Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713426/
https://www.ncbi.nlm.nih.gov/pubmed/33273479
http://dx.doi.org/10.1038/s41467-020-19864-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713426/
https://www.ncbi.nlm.nih.gov/pubmed/33273479
http://dx.doi.org/10.1038/s41467-020-19864-w

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