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Anti-IL-17A treatment reduces serum inflammatory, angiogenic and tissue remodeling biomarkers accompanied by less synovial high endothelial venules in peripheral spondyloarthritis

Spondyloarthritis (SpA) is characterized by inflammation and new bone formation. The exact pathophysiology underlying these processes remains elusive. We propose that the extensive neoangiogenesis in SpA could play a role both in sustaining/enhancing inflammation and in new bone formation. While amp...

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Detalles Bibliográficos
Autores principales: Kaaij, Merlijn H., Helder, Boy, van Mens, Leonieke J. J., van de Sande, Marleen G. H., Baeten, Dominique L. P., Tas, Sander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713433/
https://www.ncbi.nlm.nih.gov/pubmed/33273664
http://dx.doi.org/10.1038/s41598-020-78204-6

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