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A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020)
In article number 2000067 Lin Yang and co‐workers find that the hydrophobic interaction between the SARS‐CoV‐2 spike protein and the ACE2 protein is significantly greater than that between the SARS‐CoV spike protein and the ACE2 protein. At the docking site, the hydrophobic portions of the hydrophil...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713555/ http://dx.doi.org/10.1002/gch2.202070121 |
| _version_ | 1783618584367333376 |
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| author | Li, Jiacheng Ma, Xiaoliang Guo, Shuai Hou, Chengyu Shi, Liping Zhang, Hongchi Zheng, Bing Liao, Chenchen Yang, Lin Ye, Lin He, Xiaodong |
| author_facet | Li, Jiacheng Ma, Xiaoliang Guo, Shuai Hou, Chengyu Shi, Liping Zhang, Hongchi Zheng, Bing Liao, Chenchen Yang, Lin Ye, Lin He, Xiaodong |
| author_sort | Li, Jiacheng |
| collection | PubMed |
| description | In article number 2000067 Lin Yang and co‐workers find that the hydrophobic interaction between the SARS‐CoV‐2 spike protein and the ACE2 protein is significantly greater than that between the SARS‐CoV spike protein and the ACE2 protein. At the docking site, the hydrophobic portions of the hydrophilic side chains of SARS‐CoV‐2 S are found to be involved in the hydrophobic interaction between the SARS‐CoV‐2 spike protein and ACE2. [Image: see text] |
| format | Online Article Text |
| id | pubmed-7713555 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77135552020-12-09 A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) Li, Jiacheng Ma, Xiaoliang Guo, Shuai Hou, Chengyu Shi, Liping Zhang, Hongchi Zheng, Bing Liao, Chenchen Yang, Lin Ye, Lin He, Xiaodong Glob Chall Cover Picture In article number 2000067 Lin Yang and co‐workers find that the hydrophobic interaction between the SARS‐CoV‐2 spike protein and the ACE2 protein is significantly greater than that between the SARS‐CoV spike protein and the ACE2 protein. At the docking site, the hydrophobic portions of the hydrophilic side chains of SARS‐CoV‐2 S are found to be involved in the hydrophobic interaction between the SARS‐CoV‐2 spike protein and ACE2. [Image: see text] John Wiley and Sons Inc. 2020-12-03 /pmc/articles/PMC7713555/ http://dx.doi.org/10.1002/gch2.202070121 Text en © 2020 Wiley‐VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Cover Picture Li, Jiacheng Ma, Xiaoliang Guo, Shuai Hou, Chengyu Shi, Liping Zhang, Hongchi Zheng, Bing Liao, Chenchen Yang, Lin Ye, Lin He, Xiaodong A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) |
| title | A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) |
| title_full | A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) |
| title_fullStr | A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) |
| title_full_unstemmed | A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) |
| title_short | A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2 (Global Challenges 12/2020) |
| title_sort | hydrophobic‐interaction‐based mechanism triggers docking between the sars‐cov‐2 spike and angiotensin‐converting enzyme 2 (global challenges 12/2020) |
| topic | Cover Picture |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713555/ http://dx.doi.org/10.1002/gch2.202070121 |
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